Author(s): Y. Krishna Reddy, Lakhpathi

Email(s): rajinisuralabs1@gmail.com

DOI: 10.5958/0975-4377.2020.00009.9   

Address: Dr Y. Krishna Reddy*, Lakhpathi
Department of Pharmaceutics, Nalanda College of Pharmacy, Jawaharlal Nehru Technological University, Hyderabad, Telangana.
*Corresponding Author

Published In:   Volume - 12,      Issue - 2,     Year - 2020


ABSTRACT:
The design of extended release tablet by using natural polymers are becoming very popular in formulating oral extended release tablet as they are biocompatible, biodegradable, non-toxic, cheap and easily available compared to synthetic polymers. The present investigation was planned to formulate and evaluate the Cephalexin extended release tablets with natural polymers like Xanthan gum, Karaya gum and Guar Gum. Drug-excipient compatibility study was conducted using FTIR spectroscopy. The procedure adopted to make the compacts was via direct compressions. The tablets were also evaluated for physicochemical characteristics and release kinetics and it was satisfactory. The developed drug delivery systems showed prolonged drug release rates over a period of 14 h. The release profile of the optimized formulation (C4) was described by the zero-order model.


Cite this article:
Y. Krishna Reddy, Lakhpathi. Formulation and Evaluation of Extended Release Tablets of an Anti-Bacterial Drug Cephalexin. Res. J. Pharma. Dosage Forms and Tech.2020; 12(2): 53-57. doi: 10.5958/0975-4377.2020.00009.9


Recomonded Articles:

Author(s): Yamunappa, Ravi Kumar, Pooja Shetty, Prathibha Suvarna, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00012.4         Access: Open Access Read More

Author(s): Patil Namrata D., Gondkar S.B., Saudagar R.B.

DOI: 10.5958/0975-4377.2016.00033.1         Access: Open Access Read More

Author(s): Swati Talokar, Rohan R Vakhariya, A.R Dhole

DOI: 10.5958/0975-4377.2017.00005.2         Access: Open Access Read More

Author(s): Rakesh P. Patel, Grishma Patel, Hitesh Patel , Ashok Baria

DOI:         Access: Open Access Read More

Author(s): Sushant R. Jagtap, D.G Phadtare, R.B. Saudagar

DOI: 10.5958/0975-4377.2016.00021.5         Access: Open Access Read More

Author(s): P. Lekshmi, K. Pramod, K.C. Ajithkumar

DOI: 10.5958/0975-4377.2016.00007.0         Access: Open Access Read More

Author(s): Yamunappa, Ravi Kumar, Pooja Shetty, Prathibha Suvarna, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00014.8         Access: Open Access Read More

Author(s): Praveen Kumar Uppala, K. Atchuta Kumar, Murali Krishna, U. Upendra Rao

DOI: 10.5958/0975-4377.2016.00039.2         Access: Open Access Read More

Author(s): Shilpa N. Shrotriya, Kishore N. Gujar, Bhakti R. Chorghe

DOI:         Access: Open Access Read More

Author(s): Sayad Basha.K, Sheema Nafees. S, Nethravani. G, Thirumalesh Naik S.B

DOI: 10.5958/0975-4377.2016.00015.X         Access: Open Access Read More

Author(s): Ashok A Hajare, Mahesh N Mali, Arun S Dange, Sushil M Sarvagod, Shweta V Patwardhan ,Sachin T Kurane

DOI:         Access: Open Access Read More

Author(s): B. Saraswathi, R. Jagadeesh Reddy, P. Swathi, G. Manasa

DOI: 10.5958/0975-4377.2017.00025.8         Access: Open Access Read More

Author(s): Alok Ranjan, Aishwarya Sahu, Akansha Yadav, Alka Payasi, Akash Jaiswal, Akshay Kumar, Akash Sahu, Ashwani Jangde, Chandrashekhar Nayak, Dev Kumar, Harshita Yarda, Mitali Sahu, Nokesh Sahu, Rajesh Patel, Nisha Nair, Mukta Agrawal, Ajazuddin, D. K. Tripathi, Amit Alexander

DOI: 10.5958/0975-4377.2018.00014.9         Access: Open Access Read More

Author(s): Ch. Anupama, P. Padmakumari, K. Abbulu, Arti Mohan, A. Ppratyusha

DOI:         Access: Open Access Read More

Author(s): Viswanadham Manasa, K.Vanitha, M. Venkataswamy, P. Prabhakar, Alluri Ramesh

DOI: 10.5958/0975-4377.2016.00002.1         Access: Open Access Read More

Author(s): Amit K. Jain, Rajput Rammulrajsinh, Pradeep Agrawal, Kinal patel

DOI:         Access: Open Access Read More

Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0975-4377 


Recent Articles




Tags