Formulation and Evaluation of Ondansetron Floating Tablet

Lokesh Patle

doi:10.5958/0975-4377.2017.00028.3

Research Journal of Pharmaceutical Dosage Forms and Technology

ISSN

0975-4377 (Online)
0975-234X (Print)

Submit Article

Formulation and Evaluation of Ondansetron Floating Tablet

Author(s): Lokesh Patle

Email(s): lokesh.patle10@gmail.com

DOI: 10.5958/0975-4377.2017.00028.3

Address: Lokesh Patle
Assistant Professor, Department of Pharmaceutics, Sardar Patel College of Technology (B. Pharmacy), Balaghat, M.P.
*Corresponding Author

Published In: Volume - 9, Issue - 4, Year - 2017

View HTML

View PDF

ABSTRACT:
Some drugs are absorbed in a particular portion of the GIT only or are absorbed to a different extent in various segments of the GIT. Such drugs are said to have an absorption window, which identifies the drug’s primary region of absorption in the GIT. Gastroretentive tablets of Ondansetron hcl were successfully prepared by effervescent technique using different gel forming polymers- HPMC (K15M, K4M, 15cps, 3cps), and carbopol 934. Formulation was optimized on basis of floating time and in vitro release. The prepared gastroretentive test formulation was found to exhibit satisfactory physico-chemical characteristics at the end of 30 days, during the stability studies. The optimized formulation was found to be stable at 400C/ 75% RH.

Keywords:

Cite this article:
Lokesh Patle. Formulation and Evaluation of Ondansetron Floating Tablet . Res. J. Pharm. Dosage Form. & Tech. 2017; 9(4): 173-179. doi: 10.5958/0975-4377.2017.00028.3

Cite(Electronic):
Lokesh Patle. Formulation and Evaluation of Ondansetron Floating Tablet . Res. J. Pharm. Dosage Form. & Tech. 2017; 9(4): 173-179. doi: 10.5958/0975-4377.2017.00028.3 Available on: https://rjpdft.com/AbstractView.aspx?PID=2017-9-4-6

Recomonded Articles:

Pharmaceutical Suspensions: Pharmacist has the Very Best Possible Formulation for the Job at Hand.

Author(s): Praneta Desale

DOI: Access: Open Access Read More

Formulation and Evaluation of Stable Montelukast Sodium Sublingual Tablet by using Lyophilization Technique

Author(s): Dipti G. Phadtare, Amol R. Pawar, R.B. Saudagar, Govind K.Patil

DOI: 10.5958/0975-4377.2017.00002.7 Access: Open Access Read More

Formulation and In-Vitro Evaluation of a Sustained Release Matrix Tablet of Telmisatan

Author(s): Hamid Khan, Javed Ali

DOI: 10.5958/0975-4377.2017.00004.0 Access: Open Access Read More

Isolation and evaluation of Basella alba linn. Leaf mucilage as release retardant in tablet formulation

Author(s): Yamunappa, Ravi Kumar, Pooja Shetty, Prathibha Suvarna, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00012.4 Access: Open Access Read More

Formulation and Evaluation of Sustained Release Matrix Tablets Containing Aceclofenac and Paracetamol

Author(s): Hamid Khan, Javed Ali

DOI: 10.5958/0975-4377.2017.00010.6 Access: Open Access Read More

Formulation and In vitro Evaluation of Immediate Release Bilayer Tablets of Telmisartan and Amlodipine Besylate

Author(s): Soham Shukla, Vikram Pandya, Praful Bhardia, Nitin Jonwal, Shashank Mishra, Deepak Bhatt, Deependra Jain

DOI: Access: Open Access Read More

Self Microemulsifying Drug Delivery System (SMEDDS): A Novel Approach to Improve the Therapeutic Efficacy of Orally Administered Drug

Author(s): Kritika Kanoujia, Chandraprabha Dewangan, Ayushi Masih, Dipti Sinha, Divya Oraon, Manisha Jaiswal, Monika Sahu, Ranjeeta Kumari, Sapna Pradhan, Ravi Suman, Rajkishan Dewangan, Roman Banjare, Pradeep Paikra, Mukesh Rawtiya, Mukta Agrawal, Ajazuddin, D. K. Tripathi, Amit Alexander

DOI: 10.5958/0975-4377.2018.00015.0 Access: Open Access Read More

Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

RNI: Not Available
DOI: 10.5958/0975-4377