The present investigation aims at development and evaluation of herbal gel using natural ingredients which gives therapeutic effect without any side effect. The gel were prepared using Carbopol with addition to the natural turmeric and glycerin (softening agent) and required amount of neem water and with no added preservative. Then Gel was adjusted to pH 7. Prepared formulation was evaluated for physical appearance, pH, spreadability, viscosity and homogeneity, skin irritation on animal model (rabbit) and anti crack (cracked heels) activity on human volunteers. ICH guidelines have followed for stability studies. Results reveal that gel showed good appearance, homogeneity, and spread ability. Viscosity is ranging between 4200 and 4500 centipoises. All formulations have shown no skin irritation to animals. The prepared gel has successfully reduced number and size of pimples during two weeks study period and cracked heels study on human volunteer. The gel was found useful in treatment of skin Rashes,edema and in skin cracks. The preparation was stable under normal storage conditions for 6 months.
Cite this article:
Vyas Jigar, Chauhan Jaydeep. Development of Multipurpose Topical Herbal Gel. Res. J. Pharma. Dosage Forms and Tech.2020; 12(2): 73-77. doi: 10.5958/0975-4377.2020.00013.0
Vyas Jigar, Chauhan Jaydeep. Development of Multipurpose Topical Herbal Gel. Res. J. Pharma. Dosage Forms and Tech.2020; 12(2): 73-77. doi: 10.5958/0975-4377.2020.00013.0 Available on: https://rjpdft.com/AbstractView.aspx?PID=2020-12-2-7