Research Journal of Pharmaceutical Dosage Forms and Technology

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0975-4377 (Online)
0975-234X (Print)


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Preparation, Characterization and Anti-Inflammatory Activity of Chitosan Stabilized Silver Nanoparticles

Author(s): S. Ram Prasad, K. Elango, S. Daisy Chellakumari, S. Dharani

Email(s): pharmacist.ramprasad@gmail.com , elangopharm16@gmail.com

DOI: Not Available

Address: S. Ram Prasad*, K. Elango, S. Daisy Chellakumari, S. Dharani
Department of Pharmaceutics, College of Pharmacy, Madras Medical College, Chennai-03.
*Corresponding Author:

Published In:   Volume - 5,      Issue - 3,     Year - 2013

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ABSTRACT:
The present study deals with preparation of silver nanoparticles using green approach such as polysaccharides method. (Chitosan was used as reducing and stabilizing agent). The prepared silver nanoparticles were characterized by UV Visible Spectroscopy, Fourier Transform Infra- red spectroscopy, Photon Correlation Spectroscopy, Scanning Electron Microscope and ICPOES. UV- Visible spectrum shows the SPR band at 420nm which confirms the formation of silver nanoparticles. The average particle size of chitosan stabilized silver nanoparticles was found to be 127.3nm. The amount of silver present in the solution was found to be 1.259mg/L using ICPOES. Chitosan stabilized silver nanoparticles were studied for anti-inflammatory activity. In vitro toxicity studies were carried out in 3T3/NIH fibroblast cell line. Using the natural environmental benign polymer chitosan, the silver nanoparticles were prepared and characterized.


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Cite this article:
S. Ram Prasad, K. Elango, S. Daisy Chellakumari, S. Dharani. Preparation, Characterization and Anti-Inflammatory Activity of Chitosan Stabilized Silver Nanoparticles. Research J. Pharma. Dosage Forms and Tech. 2013; 5(3): 161-167.

Cite(Electronic):
S. Ram Prasad, K. Elango, S. Daisy Chellakumari, S. Dharani. Preparation, Characterization and Anti-Inflammatory Activity of Chitosan Stabilized Silver Nanoparticles. Research J. Pharma. Dosage Forms and Tech. 2013; 5(3): 161-167.   Available on: https://rjpdft.com/AbstractView.aspx?PID=2013-5-3-8


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DOI: 10.5958/0975-4377 

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Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. The aim of RJPDFT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPDFT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical Chemistry, Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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