Research Journal of Pharmaceutical Dosage Forms and Technology

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0975-4377 (Online)
0975-234X (Print)


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Ambroxol Lozenges: Introduction and Recent Advances

Author(s): Shoaib Ahmad

Email(s): shoaibahmad1999@gmail.com

DOI: 10.5958/0975-4377.2016.00041.0   

Address: Dr. Shoaib Ahmad
University School of Pharmaceutical Sciences, Rayat-Bahra University, Mohali 140104 India
*Corresponding Author

Published In:   Volume - 8,      Issue - 4,     Year - 2016

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ABSTRACT:
Ambroxol hydrochloride (trans-4-[(2-amino-3,5-dibrom-benzyl)amino]cyclohexano hydrochloride; CAS 18683-91-5) is a mucolytic agent. It is an ingredient of several cough and cold formulations – particularly syrups and tablets. The pharmacological properties (i.e. anesthetic, analgesic and anti-inflammatory) have aroused the interest of the scientific community in this molecule. As a result, many studies have focused on the formulation of the lozenges of ambroxol hydrochloride. The commercial marketing of these lozenges started in the year 2002. The reported strengths of these lozenges are 15, 20, and 30 mg. The studies have indicated that bioavailability of the drug from lozenges is better than the tablets. It is so apparently because dissolution of the lozenges in the mouth itself adds to the systemic circulation. Hence, the lozenges can be better candidate for treating respiratory tract problems and associated symptoms. The lozenges are usually well tolerated. The present communication is an attempt to present an overview of the recent developments concerning ambroxol hydrochloride lozenges.


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Cite this article:
Shoaib Ahmad. Ambroxol Lozenges: Introduction and Recent Advances. Res. J. Pharm. Dosage Form. & Tech. 2016; 8(4): 296-297. doi: 10.5958/0975-4377.2016.00041.0

Cite(Electronic):
Shoaib Ahmad. Ambroxol Lozenges: Introduction and Recent Advances. Res. J. Pharm. Dosage Form. & Tech. 2016; 8(4): 296-297. doi: 10.5958/0975-4377.2016.00041.0   Available on: https://rjpdft.com/AbstractView.aspx?PID=2016-8-4-10


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Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. The aim of RJPDFT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPDFT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical Chemistry, Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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