Author(s): Bagul Mahesh B., Surawase Rajendra K.

Email(s): bagulmahesh12245@gmail.com

DOI: 10.52711/0975-4377.2022.00049   

Address: Bagul Mahesh B.*, Surawase Rajendra K.
Department of Pharmaceutics, Loknete Dr. J. D. Pawar College of Pharmacy, Manur, Tal. Kalwan - 423501, Dist. Nashik, (MH) India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 4,     Year - 2022


ABSTRACT:
This look at aimed to increase the system of effervescent tablet containing zinc Gluconate and Ascorbic acid (vit c) combination to increase immunity and likely through reducing viral load and improving immunity of the patients. In this examine the formula turned into calculated exactly and then prepared by way of two distinct srtategies for compression and assessment. The flowability of powder and grannules turned into investigated effervescent tablet were produced by way of direct compression and wet granulation approach. The produced tablet have been then evaluated for appropriate hardness, friability ?1%, effervescent time ? 3 minutes, solution PH ?6, water content ? 0.5% and most beneficial content uniformity. The powder aggregate prepared for the direct compression technique had acceptable flowability however required a excessive compression force. Flowability and different physicochemical properties of this powder. Including compressibility and hardness have been progressed with the aid of granulation. The result of effervescent tablet produced by way of the moist granulation technique, which incorporate a higher percent of granulated content material have been higher than other method. The PVP-K30 binder solution is suitable to produced bubbling granules which are compressed into tablet, because of improvement in flowability and compactibility.


Cite this article:
Bagul Mahesh B., Surawase Rajendra K.. Development of Zinc Gluconate Vitamin C Effervescent Tablet for Immunity Improvement and Management of COVID-19. Research Journal of Pharmaceutical Dosage Forms and Technology. 2022; 14(4):299-3. doi: 10.52711/0975-4377.2022.00049

Cite(Electronic):
Bagul Mahesh B., Surawase Rajendra K.. Development of Zinc Gluconate Vitamin C Effervescent Tablet for Immunity Improvement and Management of COVID-19. Research Journal of Pharmaceutical Dosage Forms and Technology. 2022; 14(4):299-3. doi: 10.52711/0975-4377.2022.00049   Available on: https://rjpdft.com/AbstractView.aspx?PID=2022-14-4-8


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