Author(s): Abhishek Kumar Singh, Kasif Shakeel

Email(s): rock.abhishekkumar00@gmail.com

DOI: 10.52711/0975-4377.2021.00046   

Address: Abhishek Kumar Singh, Kasif Shakeel
Aryakul College of Pharmacy and Research, Natkur, P.O.: Chandrawal Aryakul College Road, Adjacent to CRPF Base Camp Lucknow- 226002, Uttar Pradesh (INDIA).
*Corresponding Author

Published In:   Volume - 13,      Issue - 4,     Year - 2021


ABSTRACT:
In the present investigation, immediate release tablet formulation of etizolam was developed for management of insomnia and anxiety using different Superdisintegrants (Sodium Starch Glycolate, Croscarmellose, Crospovidone), Povidone K-30 and Magnesium stearate by wet granulation method. The drug-excipients interaction was investigated by UV spectrophotometer. The granules and tablets of Etizolam were evaluated for various pre and post compression parameters like angle of repose, compressibility index, hausners ratio, tablet hardness, friability and in vitro disintegration and dissolution studies and their results were found to be satisfactory. These results suggest that maximum in vitro dissolution profile of formulation F6 were found to have equivalent percentage of drug release and concluded that F6 is better and similar to innovator product.


Cite this article:
Abhishek Kumar Singh, Kasif Shakeel. Formulation and Evaluation of Immediate Release Tablets of Etizolam. Research Journal of Pharmaceutical Dosage Forms and Technology. 2021; 13(4):281-4. doi: 10.52711/0975-4377.2021.00046

Cite(Electronic):
Abhishek Kumar Singh, Kasif Shakeel. Formulation and Evaluation of Immediate Release Tablets of Etizolam. Research Journal of Pharmaceutical Dosage Forms and Technology. 2021; 13(4):281-4. doi: 10.52711/0975-4377.2021.00046   Available on: https://rjpdft.com/AbstractView.aspx?PID=2021-13-4-3


REFERENCES:
1.    Y. Fu, S. Yang, S.H. Jeong, S. Kimura, K. Park, Crit: Rev Ther Drug Carrier Syst, 2004, 21: 433- 476.
2.    Shishu, A.Bhatti, Indian Drugs, 2006, 43: 643- 648
3.    D. Douroumis D, Expert.Opin Drug Deliv, 2007, 4: 417-426.
4.    Y. Katsuragi, Y. Sugiura, C.Lee, K.Otsuji, K.Kurihara, Pharm Res, 1995, 12: 658-662.
5.    Rang and Dale’s Pharamcology, 2008; Sixth Edition, 685-687.
6.    British Pharmacopoeia 2005, Vol. I, Published by the Stationery Office, London. 2005; 697- 698.
7.    Fukuoka H, Ishibashi Y, Shiba T, Tuchiya F, Sakanishi S: Clinical study of allylestrenol (Perselin) on patients with prostatic hypertrophy. Hinyokika Kiyo. Acta Urologica Japonica, 1993; 39: 679-683
8.    Aulton M, Pharmaceutics: The Science of Dosage form Design International Student Edition, Published by Churchil Livingstone, 2001; 304-321 and 347-668.
9.    Banker GS, Modern Pharmaceutics, Marcel Dekker Inc, Newyork, Third Editon, 2002; 576-820.
10.    Lachman Liberman H and Kanig J, the Theory of Practice of Industrial Pharmacy, Published by Lea and Febiger, Third Edition 1986; 293-345,346-373.
11.    Remington J, Remington :2005, the Science and Practice of Pharmacy, published by Lippincott Williams and Wilikins., Nineteenth Edition.
12.    Kuchekar B.S., BhisesS.B., Arumugam V Indian J Pharm., Educ., Second Edition, 2001; 150-152.

Recomonded Articles:

Author(s): Gopal Rao M., M. A. Amutha Gnana Arasi, S. Jayaprakash, M. Arun Kumar, P. Kavitha

DOI:         Access: Open Access Read More

Author(s): Yamunappa, Ravi Kumar, Pooja Shetty, Prathibha Suvarna, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00012.4         Access: Open Access Read More

Author(s): Simila Madathil, RaviKumar, Anju Govind, Mercy Mathew, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00013.6         Access: Open Access Read More

Author(s): Soham Shukla, Vikram Pandya, Praful Bhardia, Nitin Jonwal, Shashank Mishra, Deepak Bhatt, Deependra Jain

DOI:         Access: Open Access Read More

Author(s): Patil Namrata D., Gondkar S.B., Saudagar R.B.

DOI: 10.5958/0975-4377.2016.00033.1         Access: Open Access Read More

Author(s): R. K.V. Naga Sudha, V. Sai Kishore, CH. Venu Babu, E. Jitendranath

DOI: 10.5958/0975-4377.2015.00016.6         Access: Open Access Read More

Author(s): Hardik B. Rana, Kajol Patel, Mansi Dholakia, Vaishali T. Thakkar, Mukesh C. Gohel, Tejal R. Gandhi

DOI: 10.5958/0975-4377.2017.00006.4         Access: Open Access Read More

Author(s): Debjit Bhowmik, Rishab Bhanot, Darsh Gautam, Parshuram Rai, K.P. Sampath Kumar

DOI: 10.5958/0975-4377.2017.00022.2         Access: Open Access Read More

Author(s): Akelesh T., R. Ramya, Venkatesh. P., Divya Jacob , R. Venkatnarayanan

DOI:         Access: Open Access Read More

Author(s): Debjit Bhowmik, Amrendra Singh , Praveen Khirwadkar, Nishi Shukla, Vikas Kumar Chaudhari

DOI: 10.5958/0975-4377.2016.00027.6         Access: Open Access Read More

Author(s): Omprasad Nayakal, Prajakta Patil, Mangesh Bhutkar, Dheeraj Randive, Somnath Bhinge

DOI: 10.5958/0975-4377.2018.00032.0         Access: Open Access Read More

Author(s): Yamunappa, Ravi Kumar, Pooja Shetty, Prathibha Suvarna, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00014.8         Access: Open Access Read More

Author(s): Sawant VA, Jayprabha P, Shende VS, Borkar SN, Wakale VS, Deore SR, Dame GY, Barve AO, Chatap VK

DOI:         Access: Open Access Read More

Author(s): Kiran Khapake, Smrutidevi H. Sonavane, Shrikrishna B. Baokar, Vinod S. Pawar, Mahesh S. Rode

DOI:         Access: Open Access Read More

Author(s): Susmitha. A, Narendra Babu. K, Imran Khan Pathan, Ishwarya. K

DOI:         Access: Open Access Read More

Author(s): V. Saikishore, G. Srikanth, Ch. Pooja, Y. Mrudula, R. Pavani, Ch. Jyosthna , C. Mayuren

DOI:         Access: Open Access Read More

Author(s): Amit K. Jain, Rajput Rammulrajsinh, Pradeep Agrawal, Kinal patel

DOI:         Access: Open Access Read More

Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0975-4377 


Recent Articles




Tags