Author(s): Abhishek Kumar Singh, Kasif Shakeel

Email(s): rock.abhishekkumar00@gmail.com

DOI: 10.52711/0975-4377.2021.00046   

Address: Abhishek Kumar Singh, Kasif Shakeel
Aryakul College of Pharmacy and Research, Natkur, P.O.: Chandrawal Aryakul College Road, Adjacent to CRPF Base Camp Lucknow- 226002, Uttar Pradesh (INDIA).
*Corresponding Author

Published In:   Volume - 13,      Issue - 4,     Year - 2021


ABSTRACT:
In the present investigation, immediate release tablet formulation of etizolam was developed for management of insomnia and anxiety using different Superdisintegrants (Sodium Starch Glycolate, Croscarmellose, Crospovidone), Povidone K-30 and Magnesium stearate by wet granulation method. The drug-excipients interaction was investigated by UV spectrophotometer. The granules and tablets of Etizolam were evaluated for various pre and post compression parameters like angle of repose, compressibility index, hausners ratio, tablet hardness, friability and in vitro disintegration and dissolution studies and their results were found to be satisfactory. These results suggest that maximum in vitro dissolution profile of formulation F6 were found to have equivalent percentage of drug release and concluded that F6 is better and similar to innovator product.


Cite this article:
Abhishek Kumar Singh, Kasif Shakeel. Formulation and Evaluation of Immediate Release Tablets of Etizolam. Research Journal of Pharmaceutical Dosage Forms and Technology. 2021; 13(4):281-4. doi: 10.52711/0975-4377.2021.00046

Cite(Electronic):
Abhishek Kumar Singh, Kasif Shakeel. Formulation and Evaluation of Immediate Release Tablets of Etizolam. Research Journal of Pharmaceutical Dosage Forms and Technology. 2021; 13(4):281-4. doi: 10.52711/0975-4377.2021.00046   Available on: https://rjpdft.com/AbstractView.aspx?PID=2021-13-4-3


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