Research Journal of Pharmaceutical Dosage Forms and Technology

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0975-4377 (Online)
0975-234X (Print)


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Formulation and Evaluation of Sustained Release Matrix Tablets using Drug Cytisine Isolated from Fava Beans to Quit Smoking

Author(s): M. Venkataswamy, Neha Thahaseen, Md Kareemuddin, JP Priyanka, Jaggareddy Gari, Manasa Reddy, Shambhuni Divyasri

Email(s): venkataswamy.m@viper.ac.in

DOI: 10.5958/0975-4377.2018.00021.6   

Address: M. Venkataswamy*, Neha Thahaseen, Md Kareemuddin, JP Priyanka, Jaggareddy Gari, Manasa Reddy, Shambhuni Divyasri
Department of Pharmaceutics, Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak, Telangana, India
*Corresponding Author

Published In:   Volume - 10,      Issue - 3,     Year - 2018

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ABSTRACT:
The aim of the present research work was to quit smoking by cytisine tablets. The tablet was formulated using excipeints by direct compression method. In vitro drug release study was carried out in simulated gastric fluid (0.1 N Hcl) for the first 2h and in phosphate buffer (pH 6.8) for the next 10 h following USP apparatus II paddle method. In order to describe the cytisine release kinetics from individual tablet formulations, the corresponding dissolution data were fitted in various kinetic dissolution models are zero order, first order. The results indicated that the drug release characteristics from follow First order kinetics and the mechanism of drug release was both Swelling and diffusion.


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Cite this article:
M. Venkataswamy, Neha Thahaseen, Md Kareemuddin, JP Priyanka, Jaggareddy Gari, Manasa Reddy, Shambhuni Divyasri. Formulation and Evaluation of Sustained Release Matrix Tablets using Drug Cytisine Isolated from Fava Beans to Quit Smoking. Res. J. Pharma. Dosage Forms and Tech.2018; 10(3):133-138. doi: 10.5958/0975-4377.2018.00021.6

Cite(Electronic):
M. Venkataswamy, Neha Thahaseen, Md Kareemuddin, JP Priyanka, Jaggareddy Gari, Manasa Reddy, Shambhuni Divyasri. Formulation and Evaluation of Sustained Release Matrix Tablets using Drug Cytisine Isolated from Fava Beans to Quit Smoking. Res. J. Pharma. Dosage Forms and Tech.2018; 10(3):133-138. doi: 10.5958/0975-4377.2018.00021.6   Available on: https://rjpdft.com/AbstractView.aspx?PID=2018-10-3-2


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Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

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Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. The aim of RJPDFT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPDFT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical Chemistry, Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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