Research Journal of Pharmaceutical Dosage Forms and Technology

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0975-4377 (Online)
0975-234X (Print)


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Minitablet: A Novel Approach for Oral Extended Release

Author(s): Shyamala Bhasakran, Preethi Sudheer

Email(s): preethiksudheer@rediffmail.com

DOI: Not Available

Address: Shyamala Bhasakran and Preethi Sudheer*
Department of Pharmaceutics, East Point College of pharmacy, Bidsrshalli, Virgo Nagar Post, Bangalore-560049, India.
*Corresponding Author

Published In:   Volume - 1,      Issue - 3,     Year - 2009

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ABSTRACT:
The present study is carried out to compare matrix tablets and mini tablets of Diltiazem hydrochloride. Matrix tablets and mini-matrix tablets containing Diltiazem hydrochloride have been prepared by wet granulation technique. The hydrophilic matrix was formed with chitosan together with the additives. Preparation, the swelling and erosion behavior, in-vitro release profiles and release kinetics and mechanism of release are discussed. Comparison of all the parameters of matrix and mini matrix tablets is discussed. The result shows that mini matrix tablets shows more extended release profile in comparison with the matrix tablets under similar conditions.


Keywords:

Cite this article:
Shyamala Bhasakran, Preethi Sudheer. Minitablet: A Novel Approach for Oral Extended Release. Research J. Pharma. Dosage Forms and Tech. 2009; 1(3):263-268 .

Cite(Electronic):
Shyamala Bhasakran, Preethi Sudheer. Minitablet: A Novel Approach for Oral Extended Release. Research J. Pharma. Dosage Forms and Tech. 2009; 1(3):263-268 .   Available on: https://rjpdft.com/AbstractView.aspx?PID=2009-1-3-22


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Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0975-4377 

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Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. The aim of RJPDFT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPDFT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical Chemistry, Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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