Author(s):
Ajay Bedadurge, Mahesh Kadare, Vinod Matole, Parikshit Shirure, Sainath Suryawanshi, Kajal Ghodake, Rohini Tikate, Vaishnavi Dhumal, Nikita Birajdar, Rohini Panchal, Nikita Madane, Sneha More, Nikita Patade, Priyanka Kamble, Sonali Potdar, Bhagyashri Dhumal, Shraddha Joshi, Sandhyarani Narvate, Sumaiyya Kunnure, Pratiksha Bondge, Aishwarya Gaikwad
Email(s):
matole7414@gmail.com
DOI:
10.52711/0975-4377.2021.00035
Address:
Ajay Bedadurge, Mahesh Kadare, Vinod Matole*, Parikshit Shirure, Sainath Suryawanshi, Kajal Ghodake, Rohini Tikate, Vaishnavi Dhumal, Nikita Birajdar, Rohini Panchal, Nikita Madane, Sneha More, Nikita Patade, Priyanka Kamble, Sonali Potdar, Bhagyashri Dhumal, Shraddha Joshi, Sandhyarani Narvate, Sumaiyya Kunnure, Pratiksha Bondge, Aishwarya Gaikwad
Shivai Charitable Trusts, College of Pharmacy, Koregaonwadi, Omerga, Maharashtra India.
*Corresponding Author
Published In:
Volume - 13,
Issue - 3,
Year - 2021
ABSTRACT:
Objective: The present research has been undertaken for the formulation and evaluation of Benzoyl Peroxide Injection. It is used for Antiacne activity. Methods: Benzoyl peroxide is used as Antiacne. Methyl paraben, Propyl paraben and benzalkoniumchloride were used as preservatives. Water for injection is used as a vehicle. The following parameters were evaluated such as clarity test, leakage test, chearity test, assay and Sterility test. Results: The clearity test shows clear solution. Drug chearity test shows no chear in the vials. Leakage test shows no leakage in the vials. pH and drug content show the F1 batch was better the other batches. IR confirmed that all functional groups are same as benzoyl Peroxide. Conclusion: It was concluded that F1 batch is the good than the other batches. So F1 batch is good for the Parenteral use.
Cite this article:
Ajay Bedadurge, Mahesh Kadare, Vinod Matole, Parikshit Shirure, Sainath Suryawanshi, Kajal Ghodake, Rohini Tikate, Vaishnavi Dhumal, Nikita Birajdar, Rohini Panchal, Nikita Madane, Sneha More, Nikita Patade, Priyanka Kamble, Sonali Potdar, Bhagyashri Dhumal, Shraddha Joshi, Sandhyarani Narvate, Sumaiyya Kunnure, Pratiksha Bondge, Aishwarya Gaikwad. Formulation and Evaluation of Benzoyl Peroxide Injection. Research Journal of Pharmaceutical Dosage Forms and Technology. 2021; 13(3):198-0. doi: 10.52711/0975-4377.2021.00035
Cite(Electronic):
Ajay Bedadurge, Mahesh Kadare, Vinod Matole, Parikshit Shirure, Sainath Suryawanshi, Kajal Ghodake, Rohini Tikate, Vaishnavi Dhumal, Nikita Birajdar, Rohini Panchal, Nikita Madane, Sneha More, Nikita Patade, Priyanka Kamble, Sonali Potdar, Bhagyashri Dhumal, Shraddha Joshi, Sandhyarani Narvate, Sumaiyya Kunnure, Pratiksha Bondge, Aishwarya Gaikwad. Formulation and Evaluation of Benzoyl Peroxide Injection. Research Journal of Pharmaceutical Dosage Forms and Technology. 2021; 13(3):198-0. doi: 10.52711/0975-4377.2021.00035 Available on: https://rjpdft.com/AbstractView.aspx?PID=2021-13-3-6
REFERENCES:
1. Del Rosso JQ. Management of truncal acne vulgaris: current perspectives on treatment. Cutis. 2006; 77(5): 285–289.
2. Tan JK, Tang J, Fung K, et al. Prevalence and severity of facial and truncal acne in a referral cohort. J Drugs Dermatol. 2008; 7(6): 551–556.
3. https://www.google.com/search?q=benzoyl+peroxide+wikipedia
4. https://www.webmd.com/skin-problems-and-treatments/picture-of-the-skin
5. Thomas S, Mahendran S, Selvakumar R. Formulation and Evaluation of An Injectable Solution as a Dosage Form.Journal of Drug Delivery and Therapeutics, 2018; 8(5): 81-87.