Author(s):
Krutika K. Wagh, Aditi Shirish Marathe, Siddhant Dipak Thakare
Email(s):
krutikawagh31@gmail.com
DOI:
10.52711/0975-4377.2026.00024 
Address:
Krutika K. Wagh, Aditi Shirish Marathe, Siddhant Dipak Thakare
Department of Pharmaceutics, Swami Institute of Pharmacy, Abhona, 423502. Maharashtra, India.
*Corresponding Author
Published In:
Volume - 18,
Issue - 2,
Year - 2026
ABSTRACT:
Two well-known prolonged-release dose forms are transdermal patches and medicated plasters (patches). These days, many reports of in vivo "adhesion lacking" are still sent to regulatory bodies, despite the fact that adequate adhesion to the skin is strictly correlated with the effectiveness and safety of the therapeutic therapy. The ability of a patch to form a bond with the surface of another material under light pressure and brief contact (tack); the adhesive's resistance to flow (shear adhesion); and the force needed to remove a patch from a surface (peel adhesion) should all be taken into account when describing the adhesive properties of a patch. Topics covered: This manuscript describes the quality control of patches and the most used techniques for measuring adhesive characteristics throughout development research. Additionally covered is the impact of formative variables on patch adhesive characteristics and their potential correlation with in vivo adhesion performances. Expert opinion: Regulatory bodies should provide appropriate recommendations to assess these qualities throughout development, and pharmacopoeias should take into account the possibility of implementing compendia testing to assay the quality of adhesive patch properties.
Cite this article:
Krutika K. Wagh, Aditi Shirish Marathe, Siddhant Dipak Thakare. Overview of Transdermal Delivery System. Research Journal of Pharmaceutical Dosage Forms and Technology. 2026; 18(2):155-2. doi: 10.52711/0975-4377.2026.00024
Cite(Electronic):
Krutika K. Wagh, Aditi Shirish Marathe, Siddhant Dipak Thakare. Overview of Transdermal Delivery System. Research Journal of Pharmaceutical Dosage Forms and Technology. 2026; 18(2):155-2. doi: 10.52711/0975-4377.2026.00024 Available on: https://rjpdft.com/AbstractView.aspx?PID=2026-18-2-10
REFERENCES:
1. Cilurzo F, Gennari CG, Minghetti P. Adhesive properties: a critical issue in transdermal patch development. Expert Opinion on Drug Delivery. 2012 Jan 1; 9(1): 33-45.
2. Dhiman S, Singh TG, RehniAK. Transdermal patches: a recent approach to new drug delivery system. Int J Pharm Pharm Sci. 2011 Sep 3; 3(5): 26-34.
3. Al Hanbali OA, Khan HM, Sarfraz M, Arafat M, Ijaz S, HameedA. Transdermal patches: Design and current approaches to painless drug delivery. Acta Pharmaceutica. 2019 Jun 30; 69(2): 197-215.
4. Pasupuleti P, Bandarapalle K, Sandhya C, Neeraja G, Afzal C, Venkataramana C, VenkatSai G. Transdermal drug delivery systems. Journal of Drug Delivery and Therapeutics. 2023 Feb 1; 13(2): 101-9.
5. WongWF, AngKP, Sethi G, Looi CY. RecentAdvancement of Medical Patch for Transdermal Drug Delivery. Medicina (Kaunas). 2023 Apr 17; 59(4): 778. doi: 10.3390/medicina59040778. PMID: 37109736; PMCID: PMC10142343.
6. Shivalingam MR, BalasubramanianAR, Ramalingam KO. Formulation and evaluation of transdermal patches of pantoprazolesodium. Int J App Pharm. 2021 Sep 7; 13(5): 287-91.
7. Jatav VS, Saggu JS, Jat RK, SharmaAK, Singh RP. Recent advances in development of transdermal patches. Pharmacophore. 2011; 2(6-2011): 251-61.
8. Patel D, Patel N, Parmar M, Kaur N. Transdermal drug delivery system: An Overview. International Journal of Toxicological and Pharmacological Research. 2011; 1: 61-80.
9. Alam MI, Alam N, Singh V, Alam MS, Ali MS, Anwer T, Safhi MM. Type, preparation and evaluation of transdermal patch: a review. World Journal of Pharmacy and Pharmaceutical Sciences. 2013 May 21; 2(4): 2199-233.
10. Jatav VS, Saggu JS, Jat RK, SharmaAK, Singh RP. Recent advances in development of transdermal patches. Pharmacophore. 2011; 2(6-2011): 251-61