Author(s): Akshay R. Yadav, Shrinivas K. Mohite

Email(s): akshayyadav24197@gmail.com

DOI: 10.5958/0975-4377.2020.00030.0   

Address: Akshay R. Yadav*, Shrinivas K. Mohite
Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Dist-Sangli, Maharashtra, India-415404.
*Corresponding Author

Published In:   Volume - 12,      Issue - 3,     Year - 2020


ABSTRACT:
SARI is the most of viral infections that cause generalised clinical symptoms that cannot be easily differentiated from other respiratory infections. Monitoring SARI cases of influenza strains such as H1N1 and Sars-Cov-2, which triggers Covid-19, helps create trends of infection nationally and enhances disease monitoring, which informs response and preparedness to containment. In present article information about genome, Clinical management of severe acute respiratory illness (SARI) in suspect/confirmed novel coronavirus (nCoV) cases by immediate implementation of appropriate IPC measures, early supportive therapy and monitoring, management of hypoxemic respiratory failure, management of septic shock and specific anti-Novel-CoV treatments were given.


Cite this article:
Akshay R. Yadav, Shrinivas K. Mohite. A Review on Severe Acute Respiratory Infection (SARI) and its Clinical Management in Suspect/ Confirmed Novel Coronavirus (nCoV) Cases. Res. J. Pharma. Dosage Forms and Tech.2020; 12(3):178-180. doi: 10.5958/0975-4377.2020.00030.0


REFERENCES:
1. Subissi L, Posthuma C, Collet A, Zevenhoven D, Gorbaleny A, Decroly E, Snijder E, Canard B, Imbert I. One severe acute respiratory syndrome coronavirus proteincomplex integrates processive RNA polymerase and exonuclease activities. Proc. Natl. Acad. Sci. USA. 2014; 111: E3900–E3909.
2. Beniac DR, Andonov A, Grudeski E, Booth TF. Architecture of the SARS coronavirus prefus on spike. Nat str mol biol. 2006; 13(8): 751–752.
3. Nal B, Chan C, Kien F, Siu L, Tse J, Chu K, Kam J, Staropoli I, Crescenzo-Chaigne B, Escriou N, van der Werf S, Yuen KY, Altmeyer R. Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E. J gen virol. 2005; 86(Pt 5): 1423–1434.
4. Gaunt ER, Hardie A, Claas ECJ, Simmonds P, Templeton KE. Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method. J Clin Microbiol. 2010; 48: 2940–2947.
5. Bhatnagar PK, Das D, Suresh MR. Molecular targets for diagnostics and therapeutics of severe acute respiratory syndrome (SARS-CoV). J Pharm Pharm Sci. 2008; 11: 1s.
6. Khan G. A novel coronavirus capable of lethal human infections: An emerging picture.  Virol J. 2013; 10: 66.
7. Dare RK, Fry AM, Chittaganpitch M, Sawanpanyalert P, Olsen SJ, Erdman DD. Human coronavirus infections in rural Thailand: A comprehensive study using real-time reverse-transcription polymerase chain reaction assays. J Infect Dis. 2007; 196: 1321–1328.
8. Dominguez SR, Robinson CC, Holmes KV. Detection of four human coronaviruses in respiratory infections in children: A one-year study in Colorado. J Med Virol. 2009; 81:1597–1604.
9. Abdul-Rasool S, Fielding BC. Understanding human coronavirus HCoV-NL63. Open Virol J. 2010; 4: 76.
10. Geller C, Varbanov M, Duval RE. Human coronaviruses: Insights into environmental exsistance and its influence on the development of new antiseptic strategies. Virus. 2012; 4: 3044–3068.
11. Corman VM, Meuller MA, Costabel U, Timm J, Binger T, Meyer B, Kreher P, Lattwein E, Eschbach-Bludau M, Nitsche A, Bleicker T, Landt O, Schweiger B, Drexler JF, Osterhaus AD, Haagmans BL, Dittmer U, Bonin F, Wolff T. Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections. Euro Surveill. 2012; 17: 49.
12.   Adachi D, Johnson G, Draker R, Ayers M, Mazzulli T, Talbot PJ, Tellier R.  Comprehensive detection and identification of human coronaviruses, including the SARS-associated coronavirus, with a single RT-PCR assay. J Virol Methods. 2004; 122: 29–36.

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