Author(s): Hamid Khan

Email(s): khanhamid770@gmail.com

DOI: 10.5958/0975-4377.2020.00040.3   

Address: Hamid Khan*
Sanskar City College of Pharmacy, Rajnandgaon, Chhattisgarh, India.
*Corresponding Author

Published In:   Volume - 12,      Issue - 4,     Year - 2020


ABSTRACT:
In the presented work formulation and in-vitro evaluation was carried out for tablets containing Valsartan as Sustained Release using HPMC and Beta-Cyclodextrin polymers by wet granulation method. The tablets were subjected to in-vitro drug release study in hydrochloric acid buffer of pH 1.2 (0.1N) with 1% w/v SLS using USP paddle apparatus. The drug released at various time intervals were determined by validated UPLC-PDA method. The prepared tablets showed better sustained release effect when compared with marketed tablets. The formulated tablets provided sustained release of Valsartan over a period of 24 h.


Cite this article:
Hamid Khan. Formulation and In-Vitro Evaluation of Sustained Release Matrix Tablets of Valsartan using Beta-Cyclodextrin. Res. J. Pharma. Dosage Forms and Tech.2020; 12(4):245-248. doi: 10.5958/0975-4377.2020.00040.3

Cite(Electronic):
Hamid Khan. Formulation and In-Vitro Evaluation of Sustained Release Matrix Tablets of Valsartan using Beta-Cyclodextrin. Res. J. Pharma. Dosage Forms and Tech.2020; 12(4):245-248. doi: 10.5958/0975-4377.2020.00040.3   Available on: https://rjpdft.com/AbstractView.aspx?PID=2020-12-4-2


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