Research Journal of Pharmaceutical Dosage Forms and Technology

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0975-4377 (Online)
0975-234X (Print)

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Formulation of Valsartan Fast Dissolving Tablets Using Novel Co Processed Superdisintegrants

Author(s): A. Pavan Kumar, V. Sai Kishore, T. E. Gopala Krishna Murthy, K. Madhu Babu,

DOI: Not Available

Address: A. Pavan Kumar*, V. Sai Kishore, T. E. Gopala Krishna Murthy and K. Madhu Babu,
Bapatla College of Pharmacy, Bapatla-522101
*Corresponding Author

Published In: Volume - 4, Issue - 1, Year - 2012

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ABSTRACT:
The present investigation deals with formulation of valsartan fast dissolving tablets using co processed superdisintegrant. Crospovidone and SSG were used for preparation of co processed superdisintegrant by physical mixing and solvent evaporation method in three different ratios (1:1, 1:2, and 1:3). Six formulations are formulated with co processed superdisintegrant and are evaluated for weight variation, hardness, wetting time, water absorption ratio, disintegration time and dissolution studies and all formulations complies with pharmacoepial standards. Formulation made with co processed crospovidone and SSG in 1:1 ratio was found to be best out of all formulations. Present investigation concludes dissolution rate of valsartan fast dissolving tablets were influenced by ratios of individual superdisintegrants employed for co processed superdisintegrant and method used for preparation of co processed superdisintegrant (physical mixing vs solvent evaporation).

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Cite this article:
A. Pavan Kumar, V. Sai Kishore, T. E. Gopala Krishna Murthy , K. Madhu Babu,. Formulation of Valsartan Fast Dissolving Tablets Using Novel Co Processed Superdisintegrants. Research J. Pharma. Dosage Forms and Tech. 2012; 4(1): 52-55 .

Cite(Electronic):
A. Pavan Kumar, V. Sai Kishore, T. E. Gopala Krishna Murthy , K. Madhu Babu,. Formulation of Valsartan Fast Dissolving Tablets Using Novel Co Processed Superdisintegrants. Research J. Pharma. Dosage Forms and Tech. 2012; 4(1): 52-55 . Available on: https://rjpdft.com/AbstractView.aspx?PID=2012-4-1-9

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Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

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DOI: 10.5958/0975-4377

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