Formulation, Evaluation and Validation of Dispersible tablet of Amoxycillin Sodium plus Cloxacillin Sodium

P.G. Bhange; A.P. Mehere; T.P. Nimbekar; P.P. Katolkar

Research Journal of Pharmaceutical Dosage Forms and Technology

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0975-4377 (Online)
0975-234X (Print)

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Formulation, Evaluation and Validation of Dispersible tablet of Amoxycillin Sodium plus Cloxacillin Sodium

Author(s): P.G. Bhange, A.P. Mehere, T.P. Nimbekar, P.P. Katolkar

Email(s): poo200511@yahoo.co.in

DOI: Not Available

Address: P.G. Bhange1*, A.P. Mehere2, T.P. Nimbekar1 and P.P. Katolkar1
1Manoharbhai Patel Institute of Pharmacy (B. Pharma), Gondia (MS) 441614
2Sharad Pawar College of Pharmacy, Wanadongri, Nagpur (MS)
*Corresponding Author

Published In: Volume - 2, Issue - 4, Year - 2010

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ABSTRACT:
Dispersible tablet of amoxicillin sodium and cloxacillin sodium were prepared by employing different superdisintegrants and disintegrants such as microcrystalline cellulose and sodium starch glycolate, crosscarmellose sodium, crosspovidon, in different concentrations by direct compression method, formulation were evaluated for the standard of dispersible tablets and were compare with marketed product. The formulated tablets fulfilled all official (I.P.) requirement of dispersible tablet and give fast dissolution of amoxicillin plus cloxacillin sodium when compared to conventional marketed tablet of same drug. Study reveals that Dispersible tablet formulated by osscarmellose sodium employing gave fastest dissolution of amoxicillin plus cloxacillin sodium.

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Cite this article:
Formulation, Evaluation and Validation of Dispersible tablet of Amoxycillin Sodium plus Cloxacillin Sodium. P.G. Bhange, A.P. Mehere, T.P. Nimbekar, P.P. Katolkar. Research J. Pharma. Dosage Forms and Tech. 2010; 2(4): 281-283.

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Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

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DOI: 10.5958/0975-4377