Author(s): B. Siddartha, I. Sudheer Babu, C. Parthiban, C. Madhavi

Email(s): siddarthabethi@rediffmail.com

DOI: Not Available

Address: B. Siddartha1*, Dr. I. Sudheer Babu2, C. Parthiban1, C. Madhavi1
1Department of Pharmaceutical Analysis, Malla Reddy College of Pharmacy, Secunderabad.
2Sir C.R. Reddy College of Pharmaceutical Sciences, Eluru.
*Corresponding Author

Published In:   Volume - 5,      Issue - 6,     Year - 2013


ABSTRACT:
A simple, precise and accurate UV Spectrophotometric method has been developed for estimation of Pantoprazole in bulk and tablet dosage form. In this method Pantoprazole shows ?max at 295nm using 0.1N NaOH as a solvent and calibration graphs were plotted over the concentrations ranging from 1 to 20µg/ml of Pantoprazole with correlation coefficient 0.999. The proposed method was validated as per ICH Q2 (R1) guidelines for precision, linearity, accuracy and recovery. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 0.083µg/ml and 0.250µg/ml respectively by simple UV spectroscopy.


Cite this article:
B. Siddartha, I. Sudheer Babu, C. Parthiban, C. Madhavi. Development and Validation of UV–Spectrophotometric Method of Pantoprazole in bulk and Pharmaceutical dosage form. Research J. Pharma. Dosage Forms and Tech. 2013; 5(6): 341-344.


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Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

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DOI: 10.5958/0975-4377 


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