Author(s): Rahul K. Godge, Prakash N. Kendre, Mahendra A. Giri, Syed M. Zama, Syed N. Lateef

Email(s): snlateef@ rediffmail.com

DOI: Not Available

Address: Rahul K. Godge, Prakash N. Kendre, Mahendra A. Giri, Syed M. Zama, Syed N. Lateef*
Sanjivani College of Pharmaceutical Education and Research, Kopargaon Dist. Ahmadnagar.(M.S.) India.
*Corresponding Author

Published In:   Volume - 1,      Issue - 1,     Year - 2009


ABSTRACT:
Tizanidine hydrochloride, the first new oral treatment for muscle spasticity in the U.S. in more than 20 years. Fast dissolving tablets are solid dosage form that contains medicinal substances and that disintegrate and dissolve rapidly without water (within seconds) when placed on the tongue. Fast dissolving tablets of Tizanidine hydrochloride were prepared by direct compression method using Sodium Starch Glycolate, Ac-Di-Sol, and Indion 414 as a super disintegrants, and controlled tablets without any super disintegrant and evaluated for hardness, friability, disintegration time, dissolution time, water absorption ratio and content uniformity. All tablets containing super disintegrants shows release of drug more than 95% within 10 minutes and controlled tablet shows release of drug after 30 minutes. Tablets containing Indion 414 as a super disintegrant shows better result compare to others. Result also shows that as the concentration of superdisintegrant increases percentage release also increases.


Cite this article:
Rahul K. Godge, Prakash N. Kendre, Mahendra A. Giri, Syed M. Zama, Syed N. Lateef. Formulation and In-Vitro Evaluation of Fast Dissolving / Disintegrating Tablets of Tizanidine Hydrochloride. Research J. Pharma. Dosage Forms and Tech. 2009; 1(1):55-58.


Recomonded Articles:

Author(s): Yamunappa, Ravi Kumar, Pooja Shetty, Prathibha Suvarna, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00012.4         Access: Open Access Read More

Author(s): Gopal Rao M., M. A. Amutha Gnana Arasi, S. Jayaprakash, M. Arun Kumar, P. Kavitha

DOI:         Access: Open Access Read More

Author(s): Simila Madathil, RaviKumar, Anju Govind, Mercy Mathew, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00013.6         Access: Open Access Read More

Author(s): Hardik B. Rana, Kajol Patel, Mansi Dholakia, Vaishali T. Thakkar, Mukesh C. Gohel, Tejal R. Gandhi

DOI: 10.5958/0975-4377.2017.00006.4         Access: Open Access Read More

Author(s): R. K.V. Naga Sudha, V. Sai Kishore, CH. Venu Babu, E. Jitendranath

DOI: 10.5958/0975-4377.2015.00016.6         Access: Open Access Read More

Author(s): Debjit Bhowmik, Rishab Bhanot, Darsh Gautam, Parshuram Rai, K.P. Sampath Kumar

DOI: 10.5958/0975-4377.2017.00022.2         Access: Open Access Read More

Author(s): Yamunappa, Ravi Kumar, Pooja Shetty, Prathibha Suvarna, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00014.8         Access: Open Access Read More

Author(s): Shilpa N. Shrotriya, Kishore N. Gujar, Bhakti R. Chorghe

DOI:         Access: Open Access Read More

Author(s): P. Lekshmi, K. Pramod, K.C. Ajithkumar

DOI: 10.5958/0975-4377.2016.00007.0         Access: Open Access Read More

Author(s): V. Saikishore, G. Srikanth, Ch. Pooja, Y. Mrudula, R. Pavani, Ch. Jyosthna , C. Mayuren

DOI:         Access: Open Access Read More

Author(s): Debjit Bhowmik, Rishab Bhanot, K.P. Sampath Kumar

DOI: 10.5958/0975-4377.2018.00036.8         Access: Closed Access Read More

Author(s): AL. Akilandeshwari , K. Elango, S. Daisy Chellakumari, S. Kishore Kumar

DOI:         Access: Open Access Read More

Author(s): Ch. Anupama, P. Padmakumari, K. Abbulu, Arti Mohan, A. Ppratyusha

DOI:         Access: Open Access Read More

Author(s): Omprasad Nayakal, Prajakta Patil, Mangesh Bhutkar, Dheeraj Randive, Somnath Bhinge

DOI: 10.5958/0975-4377.2018.00032.0         Access: Closed Access Read More

Author(s): Priti Trivedi, Shailendra Bhatt

DOI:         Access: Open Access Read More

Author(s): K Sonu Sharma, Rashmi Sharma, G Vidya Sagar

DOI:         Access: Open Access Read More

Author(s): Priyanka Choudhury, Pulak Deb, Suvakanta Dash

DOI: 10.5958/0975-4377.2016.00025.2         Access: Open Access Read More

Author(s): Prithviraj Chakraborty, Kumar Suresh, Veera Garg , Anu Goyal

DOI:         Access: Open Access Read More

Author(s): Ravi Kumar, Swati Patil, M. B. Patil, Sachin R. Patil, Mahesh S. Paschapur

DOI:         Access: Open Access Read More

Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0975-4377 


Recent Articles




Tags