The purpose of writing this review on importance of floating drug delivery systems (FDDS) was to compile the recent literature with special focus on the principle mechanism to achieve gastric retention. Floating drug delivery systems are mainly dependent upon the different type of polymers and role of polymer. Floating drug delivery systems is the important approach to achieve gastric retention to obtain sufficient drug bioavailability. Floating drug delivery system is based on the gastroretentive drug delivery systems. These systems are useful to several problems encountered during the development of a pharmaceutical dosage form. Floating systems are low density systems that have sufficient buoyancy to float over the gastric contents and remain in the stomach for a prolonged period. While the system floats over the gastric contents, the drug is released slowly at the desired rate, which results in increased gastro-retention time and reduces fluctuation. This review also summarizes the in vitro techniques, in vivo studies to evaluate the performance and application of floating systems and application of these systems.
Cite this article:
Yashpal Singh Chauhan, Udichi Kataria, Ashok Dashora. Importance of Floating Drug Delivery System. Res. J. Pharm. Dosage Form. & Tech. 2018; 10(4): 220-232. doi: 10.5958/0975-4377.2018.00034.4