Research Journal of Pharmaceutical Dosage Forms and Technology

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0975-4377 (Online)
0975-234X (Print)


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Evaluation Study of Sustained Release Ocular Insert of Brimonidine Tartrate and Timolol

Author(s): R. Z. Mujoriya, M. D. Kshirsagar

Email(s): raj_mujoriya@live.com

DOI: 10.5958/0975-4377.2016.00032.X   

Address: R. Z. Mujoriya1*, Dr. M. D. Kshirsagar2
1Research Scholar, P. Wadhawani College of Pharmacy, Yeotmal
2Professor, P. Wadhawani College of Pharmacy, Yeotmal
*Corresponding Author

Published In:   Volume - 8,      Issue - 4,     Year - 2016

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ABSTRACT:
The present work showed that incorporation of hydrophilic polymer into hydrophobic matrix system can be successfully done in order to model ocular inserts of Brimonidine Tartrate and Timolol providing promising controlled release delivery system. The control of IOP, systemic absorption and hence possible side effects using inserts was found to be better than conventional eye drops. Thus, on the basis of in-vivo anti-glaucoma activity, ocular safety test and stability studies, it can be concluded that this ocular insert can be a promising once-a-day controlled release formulation after due considerations of human in vivo studies.


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Cite this article:
R. Z. Mujoriya, M. D. Kshirsagar. Evaluation Study of Sustained Release Ocular Insert of Brimonidine Tartrate and Timolol. Res. J. Pharm. Dosage Form. & Tech. 2016; 8(4): 231-236. doi: 10.5958/0975-4377.2016.00032.X

Cite(Electronic):
R. Z. Mujoriya, M. D. Kshirsagar. Evaluation Study of Sustained Release Ocular Insert of Brimonidine Tartrate and Timolol. Res. J. Pharm. Dosage Form. & Tech. 2016; 8(4): 231-236. doi: 10.5958/0975-4377.2016.00032.X   Available on: https://rjpdft.com/AbstractView.aspx?PID=2016-8-4-1


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Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

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DOI: 10.5958/0975-4377 

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Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. The aim of RJPDFT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPDFT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical Chemistry, Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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