Research Journal of Pharmaceutical Dosage Forms and Technology

ISSN

0975-4377 (Online)
0975-234X (Print)


Submit Article

Evaluation Study of Sustained Release Ocular Insert of Brimonidine Tartrate and Timolol

Author(s): R. Z. Mujoriya, M. D. Kshirsagar

Email(s): raj_mujoriya@live.com

DOI: 10.5958/0975-4377.2016.00032.X   

Address: R. Z. Mujoriya1*, Dr. M. D. Kshirsagar2
1Research Scholar, P. Wadhawani College of Pharmacy, Yeotmal
2Professor, P. Wadhawani College of Pharmacy, Yeotmal
*Corresponding Author

Published In:   Volume - 8,      Issue - 4,     Year - 2016

 View HTML        View PDF

ABSTRACT:
The present work showed that incorporation of hydrophilic polymer into hydrophobic matrix system can be successfully done in order to model ocular inserts of Brimonidine Tartrate and Timolol providing promising controlled release delivery system. The control of IOP, systemic absorption and hence possible side effects using inserts was found to be better than conventional eye drops. Thus, on the basis of in-vivo anti-glaucoma activity, ocular safety test and stability studies, it can be concluded that this ocular insert can be a promising once-a-day controlled release formulation after due considerations of human in vivo studies.


Keywords:

Cite this article:
R. Z. Mujoriya, M. D. Kshirsagar. Evaluation Study of Sustained Release Ocular Insert of Brimonidine Tartrate and Timolol. Res. J. Pharm. Dosage Form. & Tech. 2016; 8(4): 231-236. doi: 10.5958/0975-4377.2016.00032.X

Cite(Electronic):
R. Z. Mujoriya, M. D. Kshirsagar. Evaluation Study of Sustained Release Ocular Insert of Brimonidine Tartrate and Timolol. Res. J. Pharm. Dosage Form. & Tech. 2016; 8(4): 231-236. doi: 10.5958/0975-4377.2016.00032.X   Available on: https://rjpdft.com/AbstractView.aspx?PID=2016-8-4-1


Recomonded Articles:

Pharmaceutical Suspensions: Pharmacist has the Very Best Possible Formulation for the Job at Hand.

Author(s): Praneta Desale

DOI:         Access: Open Access Read More

Formulation and Evaluation of Stable Montelukast Sodium Sublingual Tablet by using Lyophilization Technique

Author(s): Dipti G. Phadtare, Amol R. Pawar, R.B. Saudagar, Govind K.Patil

DOI: 10.5958/0975-4377.2017.00002.7         Access: Open Access Read More

Formulation and In-Vitro Evaluation of a Sustained Release Matrix Tablet of Telmisatan

Author(s): Hamid Khan, Javed Ali

DOI: 10.5958/0975-4377.2017.00004.0         Access: Open Access Read More

Isolation and evaluation of Basella alba linn. Leaf mucilage as release retardant in tablet formulation

Author(s): Yamunappa, Ravi Kumar, Pooja Shetty, Prathibha Suvarna, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00012.4         Access: Open Access Read More

Formulation and Evaluation of Sustained Release Matrix Tablets Containing Aceclofenac and Paracetamol

Author(s): Hamid Khan, Javed Ali

DOI: 10.5958/0975-4377.2017.00010.6         Access: Open Access Read More

Formulation and Evaluation of Transdermal Patch of Aceclofenac

Author(s): Rakesh P. Patel, Grishma Patel, Hitesh Patel , Ashok Baria

DOI:         Access: Open Access Read More

Formulation and In vitro Evaluation of Immediate Release Bilayer Tablets of Telmisartan and Amlodipine Besylate

Author(s): Soham Shukla, Vikram Pandya, Praful Bhardia, Nitin Jonwal, Shashank Mishra, Deepak Bhatt, Deependra Jain

DOI:         Access: Open Access Read More

Development of Multipurpose Topical Herbal Gel

Author(s): Vyas Jigar, Chauhan Jaydeep

DOI: 10.5958/0975-4377.2020.00013.0         Access: Open Access Read More

Formulation and Evaluation of Ondansetron Floating Tablet

Author(s): Lokesh Patle

DOI: 10.5958/0975-4377.2017.00028.3         Access: Open Access Read More

Formulation Development of Ketoconazole Ophthalmic Formulation

Author(s): Varsha R. Sandhan, S.B. Gondkar, R. B. Saudagar

DOI:         Access: Open Access Read More

Formulation and Evaluation of Mycophenolate mofetil Capsules

Author(s): Akelesh T., R. Ramya, Venkatesh. P., Divya Jacob , R. Venkatnarayanan

DOI:         Access: Open Access Read More

Stability Testing of Pharmaceutical Products

Author(s): Yashpal Singh Chauhan, Ravi Nex, Ghanshyam Sevak, Mahendra Singh Rathore

DOI: 10.52711/0975-4377.2021.00052         Access: Open Access Read More

Formulation and Evaluation of Immediate Release Pravastatin Sodium Tablets

Author(s): Yamunappa, Ravi Kumar, Pooja Shetty, Prathibha Suvarna, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00014.8         Access: Open Access Read More

Formulation Development and Evaluation of Buccal Patches of Aceclofenac for Gingivitis

Author(s): Puja Saha, Pratik Swarup Das

DOI: 10.5958/0975-4377.2017.00026.X         Access: Open Access Read More

Development and Optimization of Floating Tablets Containing Rebamipide

Author(s): Jigar Vyas, Jai Mehta, Neha Pal, Kapil Daxini

DOI: 10.5958/0975-4377.2020.00002.6         Access: Open Access Read More

Glimepiride Micro balloons: A Novel Approach for Bioavailability Enhancement by Gastro-Retentive Floating Drug Delivery System

Author(s): Rutuja R. Shah, Rutuja S. Shah, Rohan R. Vakhariya

DOI: 10.5958/0975-4377.2017.00030.1         Access: Open Access Read More

Taste Abatement of Hydroxyzine Hydrochloride by Cation Exchange Resins

Author(s): Pawar P.B. , Wagh M.P , Hiremath S.N, Baviskar A.V, Akul M.R.

DOI:         Access: Open Access Read More

Studies on Influence of Process and Formulation Variables on Performance of Omeprazole Pellets

Author(s): B. Soujanya, G. Pavani Priya, T.E.G.K.Murthy

DOI: 10.5958/0975-4377.2015.00005.1         Access: Open Access Read More

Design and Evaluation of Sustained Release Matrix Tablets of Ibuprofen

Author(s): Amit K. Jain, Rajput Rammulrajsinh, Pradeep Agrawal, Kinal patel

DOI:         Access: Open Access Read More

Formulation and Evaluation of Aqueous Enteric Coated Delayed Release Omeprazole Pellets

Author(s): Viswanadham Manasa, K.Vanitha, M. Venkataswamy, P. Prabhakar, Alluri Ramesh

DOI: 10.5958/0975-4377.2016.00002.1         Access: Open Access Read More

Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0975-4377 

Quick Links


Latest Issues

Popular Articles


Recent Articles



Formulation Development and Evaluation of Topical Herbal Emulgel of Turmeric
Evaluation and Preparation of Aloe Vera Gel: Benefits and Testing Methods
Redefining Immunization: Recent Advances and Innovations in Vaccine Development
Formulating and Analyzing Box-Behnken-designed Sustained Release Beads for Perindopril Erbumine
Formulation Development and Evaluation of Pantoprazole Floating Tablet by using 2 Level Factorial Design
Detailed Review of Shatdhaut Ghrita as a Base in Moisturizing Cream
The Exosome Revolution: Bridging Early Detection and Personalized Treatment
AI-Powered Formulation Design: Neural Networks in Drug Development
Naegleria fowleri: An Amoeba That Eats your Brain
Enhancing Environmental Health: The Role of Chemical Flocculation in Wastewater Remediation
Liposomal In Situ Gel: A Novel Approach for the Treatment of Parkinson
Nanocochleate A Novel Drug Delivery System
Formulation Development and Evaluation of Quetiapine fumarate Extended-Release tablet by using 23 Factorial designs
Psychobiotics: An Emerging Solution for Alleviation of Psychotic Disorders
Medicinal Effect of Curcumin as an Anti-tuberculosis
Health Benefits of Herbal Plants in Nutraceuticals
Development and Evaluation of Bilayer Tablets of Bimodal release of Bisoprolol Fumarate
Formulation, Development and Evaluation of Famotidine Orodispersible Tablets
Formulation Development and Evaluation of Natural Facewash Powder
Analysis of Antioxidant and Prebiotic Properties of Selected Seed Extracts for Potential Nutraceutical Applications

Tags


About Journal

Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. The aim of RJPDFT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPDFT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical Chemistry, Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
Read More  

Visitors

Today: 1030
Yesterday: 1203
Total: 1083019