ABSTRACT:
In current scenario medical experts have long struggled with how to deliver medication to targeted location into the body while also controlling the drug release rate to avoid overdosing. This issue may be resolve through the creation of novel, intricate formulation known as nano sponges. Nano sponges are small sponge, all around size virus, that may hold a range of medication. These microscopic sponges can move through the system until they reach the intended target region, where they adhere to surface and start to release the drug in steady and controlled manner. Nano sponges are a network or 3D polyester scaffold that are spontaneously decompose. These polyesters are combined with cross-linkers agent in a solution to create a nano sponge. When loaded nano sponge’s framework breakdown the drug particle is released. They are mostly in solid form and it can be formulated as oral, parenteral, topical, or inhalation dosage form, several studies havebeen conducted on protein, peptide, genes, anti-cancer biomolecules via nano-particle technology which hep to reduce undesirable effect and enhance efficacy.
Cite this article:
Rikhav Shah, Dipika Chavda. Nano Sponge: An Emerging Nano-Technology Based Drug Delivery System. Research Journal of Pharmaceutical Dosage Forms and Technology.2024; 16(1):67-5. doi: 10.52711/0975-4377.2024.00012
Cite(Electronic):
Rikhav Shah, Dipika Chavda. Nano Sponge: An Emerging Nano-Technology Based Drug Delivery System. Research Journal of Pharmaceutical Dosage Forms and Technology.2024; 16(1):67-5. doi: 10.52711/0975-4377.2024.00012 Available on: https://rjpdft.com/AbstractView.aspx?PID=2024-16-1-12
REFRENCES:
1. Bhowmik H, venkatesh DN, Kuila A, Kumar KH. Nanosponges: a review. 2018; 10(4): 3–7.
2. Kimbonguila A, Matos L, Petit J, Scher J, Nzikou JM. Effect of physical treatment on the physicochemical, rheological and functional properties of yam meal of the cultivar “ngumvu” from dioscorea alata l. of congo. Int J Recent Sci Res. 2019; 10(c): 30693–5.
3. Bilal J. S, Abhishek S. P, Ankush S. B, Indrayani D. R, Manojkumar M. N. Nanosponges: an evolutionary trend for targeted drug delivery. Int J Pharm Sci Med. 2021; 6(6): 1–14.
4. Alongi J, Poskovic M, Frache A, Trotta F. Role of cyclodextrin nanosponges in polypropylene photooxidation. Carbohydr polym [internet]. 2011; 86(1):127–35. : http://dx.doi.org/10.1016/j.carbpol.2011.04.022
5. Pawar AY, Naik AK, Jadhav KR. Nanosponges: a novel drug delivery system. Asian J Pharm. 2016;10(4):s456–63.
6. Ghurghure SM, Sana M, Pathan A, Surwase PR. Nanosponges: a novel approach for Targeted Drug Delivery System. 2018;15–23.
7. Tejashri G, Amrita B, Darshana J. Cyclodextrin based nanosponges for pharmaceutical use: a review. 2013; 63: 335–58.
8. Muni Raja Lakshmi K, Suma Shree C, Lakshmi Priya N. Nano sponges: a novel approach for targeted drug delivery systems. J Drug Deliv Ther. 2021; 11(2): 247–52.
9. Pawar S, Shende P, Trotta F, Shende P, Trotta F. Accepted manuscript. 2019;
10. Jyoti P, Tulsi B, Popin K, Chetna B, Jyoti P. An innovative advancement for targeted drug delivery : nanosponges. 2016; 6(2): 59–64.
11. Sherje AP, Dravyakar BR, Kadam D, Jadhav M. Cyclodextrin-based nanosponges: a critical review. Carbohydr polym [internet]. 2017; 173(1): 37–49. Available from: http://dx.doi.org/10.1016/j.carbpol.2017.05.086
12. Yadav RP, Sheeba FR. Nanosponges - overview. Asian j pharm technol [internet]. 2022 mar 5 [cited 2023 aug 8];12(1):76–76. Available from: https://ajptonline.com/abstractview.aspx?pid=2022-12-1-12
13. Ravi SC, Krishnakumar K, Nair SK. Nano sponges: a targeted drug delivery system and its applications. Gsc Biol Pharm Sci. 2019; 7(3): 40–7.
14. Article R, Bachkar BA, Gadhe LT, Battase P, Mahajan N, Wagh R, et al. Nanosponges: a potential nanocarrier for targeted. 2015; 4(3): 751–68.
15. Sadhasivam J, Sugumaran A, Narayanaswamy D. Nano sponges: a potential drug delivery approach. Res J Pharm Technol. 2020; 13(7): 3442–8.
16. Kaur S, Kumar S. Nanosponges: An innovative drug delivery system. 2019;12.
17. Pravin P, Adhikrao Y, Varsha G. Different techniques for preparation of nanosuspension with reference to its characterisation and various applications - a review. Asian J Res Pharm Sci. 2018; 8(4): 210–6.
18. Penjuri SCB, Ravouru N, Damineni S, BNS S, Poreddy sr. Lasoprazol yüklü nanosüngerlerin formülasyonu ve değerlendirilmesi. Turkish J Pharm Sci. 2016; 13(3): 304–10.
19. Bolmal UB, Manvi F V, Kotha R, Palla SS, Paladugu A, Reddy KR. Recent advances in nanosponges as drug delivery system. Int j Pharm Sci Nanotechnol. 2013; 6(1): 1934–44.
20. Chilajwar S V, Pednekar PP, Jadhav KR, Kadam VJ. Cyclodextrin-based nanosponges: a propitious platform for Enhancing Drug Delivery. 2014; 111–20.
21. Vishwakarma A, Nikam P, Mogal R, Talele S. Review on nanosponges: a benefication for novel drug delivery. 2014; 6(1): 11–20.
22. Panda S, Vijayalakshmi S, Pattnaik S, Swain RP. Nanosponges: a novel carrier for targeted drug delivery. Int J Pharmtech Res. 2015; 8(7): 213–24.
23. Satishs. Sathish Kumar GM. Asian Journal of Pharmacy and technology [internet]. [cited 2023 aug 8]. Available from: https://ajptonline.com/htmlpaper.aspx?journal=asian+journal+of+pharmacy+and+technology%3bpid%3d2014-4-1-2
24. Rajam RP, Muthukumar KR. An updated comprehensive review on nanosponges – novel emerging drug delivery system. Res J Pharm Technol. 2021; 14(8): 4476–84. Available from: https://rjptonline.org/abstractview.aspx?pid=2021-14-8-84
25. Sri KV, Santhoshini G, Sankar DR, Niharika K. Formulation and evaluation of rutin loaded nanosponges. Asian J Res Pharm Sci. 2018; 8(1): 21–4. : https://ajpsonline.com/abstractview.aspx?pid=2018-8-1-5
26. Anandam S, Selvamuthukumar S. Optimization of microwave-assisted synthesis of cyclodextrin nanosponges using response surface Methodology. 2014;
27. John D, Francis E, Yusuf FS. Research article development and evaluation of nanosponges loaded extended release tablets of lansoprazole. 2019;24–8.
28. Nitish, Jeganath S, Abdelmagid KFK. A review on nanosponges – a promising novel drug delivery system. Res J Pharm Technol 2021;14(1): 501–5. Available from: https://rjptonline.org/abstractview.aspx?pid=2021-14-1-91
29. Yadav GV, Panchory HP. “Nanosponges – a boon to the targeted drug delivery system.” J Drug Deliv Ther. 2013; 3(4):151–5.
30. Journals H, Article R. Nanosponges: a new approach for drug Targetting. 2016; 3.
31. Behura PR, Krishna V. A novel revolutionary approach of a synthesis and application of targeted nanosponge drug delivery. J Appl Pharm, 2021; 13(6): 297.
32. Krabicov I, Appleton SL, Tannous M, Hoti G, Caldera F, Pedrazzo AR, et al. History of cyclodextrin nanosponges. :1–23.
33. Ravi G, Bose PSC, Ravi V, Sarita D. Preparation, characterization and evaluation of celecoxib loaded nanosponges for the treatment of psoriatic arthritis. Int J Med Biomed Stud. 2019; 3(12): 181–5.
34. Shringirishi M, Mahor A, Gupta R, Prajapati SK, Bansal K, Kesharwani P. Fabrication and characterization of nifedipine loaded β-cyclodextrin nanosponges: an in vitro and in vivo evaluation. J Drug Deliv Sci Technol. 2017; 41:344–50. Available from: http://dx.doi.org/10.1016/j.jddst.2017.08.005