Author(s): Prakash Nathaniel Kumar Sarella, Anil Kumar Vipparthi, Surekha Valluri, Srujala Vegi, Veera Kumari Vendi

Email(s): E-mail:

DOI: 10.52711/0975-4377.2024.00014   

Address: Prakash Nathaniel Kumar Sarella*, Anil Kumar Vipparthi, Surekha Valluri, Srujala Vegi, Veera Kumari Vendi
Department of Pharmaceutics, Aditya College of Pharmacy, ADB Road, Surampalem, Kakinada 533437, Andhra Pradesh, India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 1,     Year - 2024


ABSTRACT:
Nanorobotics, a rapidly evolving field at the intersection of nanotechnology and robotics, holds immense promise in revolutionizing pharmaceutical drug delivery and development. This comprehensive review article explores the various facets of nanorobotics and its pivotal role in the advancement of medicine. The article begins with an introduction to nanorobotics, providing a definition and historical background to contextualize its significance. Subsequently, it delves into nanorobotics' role in drug delivery, highlighting the challenges faced in conventional methods and the advantages of employing nanorobot-based systems. The review further explores nanorobotics in drug development, emphasizing its contribution to accelerating drug discovery and enabling personalized medicine. It discusses the different types of nanorobots utilized in pharmaceutical applications, including molecular, cellular, and hybrid systems. Additionally, the article covers the fabrication and propulsion techniques of nanorobots, along with navigation and control strategies. Furthermore, it delves into the interaction of nanorobots with biological systems and their potential applications in site-specific drug delivery and disease treatment. Ethical and regulatory considerations pertinent to nanorobotics in pharmaceuticals are also addressed. Finally, the review offers insights into future perspectives and challenges in the field, envisioning advanced drug delivery systems, targeted therapies, nanorobot swarms, and biohybrids. By comprehensively examining the subject, this review article presents a holistic understanding of nanorobotics potential in reshaping pharmaceutical practices for precision medicine and improved patient outcomes.


Cite this article:
Prakash Nathaniel Kumar Sarella, Anil Kumar Vipparthi, Surekha Valluri, Srujala Vegi, Veera Kumari Vendi. Nanorobotics: Pioneering Drug Delivery and Development in Pharmaceuticals. Research Journal of Pharmaceutical Dosage Forms and Technology.2024; 16(1):81-0. doi: 10.52711/0975-4377.2024.00014

Cite(Electronic):
Prakash Nathaniel Kumar Sarella, Anil Kumar Vipparthi, Surekha Valluri, Srujala Vegi, Veera Kumari Vendi. Nanorobotics: Pioneering Drug Delivery and Development in Pharmaceuticals. Research Journal of Pharmaceutical Dosage Forms and Technology.2024; 16(1):81-0. doi: 10.52711/0975-4377.2024.00014   Available on: https://rjpdft.com/AbstractView.aspx?PID=2024-16-1-14


REFERENCES:
1.    Hey A. Feynman and Computation. CRC Press; 2018.
2.    Homberger M, Simon U. On the application potential of gold nanoparticles in nanoelectronics and biomedicine. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 2010; 368(1915): 1405-53. doi: 10.1098/rsta.2009.0275
3.    Baswaraj D, Vasanthi MZ, Deepthi S. Effect of Nanotechnology. International Journal of Computer Technology and Applications 2012; 3(4).
4.    Upadhyay RK. Drug Delivery Systems, CNS Protection, and the Blood Brain Barrier. Biomed Res Int 2014; 2014: 869269. doi: 10.1155/2014/869269
5.    Patil LB, Patil SS, Nitalikar MM, Magdum CS, Mohite SK. A Review on-Novel Approaches in Nanorobotics. Asian Jour Pharmac Rese 2016; 6(4): 217. doi: 10.5958/2231-5691.2016.00030.7
6.    S. Patel S, N. Patel P. A Brief Review on Nanorobotics Applications in Medicine and Future Prospects. AJPS Published online March 21, 2023: 19-28. doi: 10.52711/2231-5659.2023.00004
7.    Abrar M, Sheikh T, Mohammed S, Ahmad FM, Shaikh U. Nanorobotics in Cancer Treatment: A Review. Rese Jour Pharmaceut Dosag Form and Technol 2019; 11(1): 43. doi: 10.5958/0975-4377.2019.00007.7
8.    Kumar R, Jha AK, Jain SK. Nanomedicine: An Emerging Area of Nanotechnology. Research Journal of Pharmaceutical Dosage Forms and Technology 2009; 1(1): 18-21.
9.    Narasimha L, Selvan A, Jairam D, Suthakaran R. Artificial red blood cells using nanotechnology. Research Journal of Pharmacy and Technology 2014; 7(11): 1323-9.
10.    Sriram K, Vishnupriya V, Gayathri R. Review on the role of Nanotechnology in Dentistry and Medicine. Rese Jour of Pharm and Technol 2016; 9(8): 1249. doi: 10.5958/0974-360X.2016.00236.5
11.    Saleh NA, Wahid TAA. Nanotechnology with X-rays plays an essential role in improving radiation therapy for malignant breast cells. Rese Jour of Pharm and Technol 2017; 10(12): 4129. doi: 10.5958/0974-360X.2017.00751.X
12.    Krishnan PRR, Sivakumar R. Nanotechnology: Modern Formulation and Evaluation Techniques -An Overview. Rese Jour of Pharm and Technol 2019; 12(8): 4039. doi: 10.5958/0974-360X.2019.00696.6
13.    Thiruchelvi R, Sikdar E, Das A, Rajakumari K. Nanobots in Today’s World. Rese Jour of Pharm and Technol. 2020; 13(4): 2033. doi: 10.5958/0974-360X.2020.00366.2
14.    Chandran A, Ammu, Merlin NJ, Dharan SS. Applications of Robotics in Urology-A Review. Asia Journ of Resear in Pharmac Scie. 2019; 9(1): 6. doi: 10.5958/2231-5659.2019.00002.X
15.    Fernandes P, Christina RC. Robotic nursing: Life saver in pandemic. Asian Journal of Nursing Education and Research. 2021; 11(2): 282-4.
16.    Tibbals HF. Medical Nanotechnology and Nanomedicine. Crc Press; 2017.
17.    Suganya K, Rethinavel Subramanian A. A survey on Nanotechnology and Its Medical Applications.
18.    Soto F, Chrostowski R. Frontiers of medical micro/nanorobotics: in vivo applications and commercialization perspectives toward clinical uses. Frontiers in Bioengineering and Biotechnology 2018; 6: 170. doi: 10.3389/fbioe.2018.00170
19.    Singh AV, Ansari MHD, Laux P, Luch A. Micro-nanorobots: important considerations when developing novel drug delivery platforms. Expert Opinion on Drug Delivery. 2019; 16(11): 1259-75. doi: 10.1080/17425247.2019.1676228
20.    Ratner MA, Ratner D. Nanotechnology: A Gentle Introduction to the next Big Idea. Prentice Hall Professional; 2003.
21.    Kumar A, Tan A, Wong J, Spagnoli JC, Lam J, Blevins BD, et al. Nanotechnology for neuroscience: promising approaches for diagnostics, therapeutics and brain activity mapping. Advanced Functional Materials. 2017; 27(39): 1700489. doi: 10.1002/adfm.201700489
22.    Jahanban-Esfahlan A, Seidi K, Jaymand M, Schmidt TL, Majdi H, Javaheri T, et al. Dynamic DNA nanostructures in biomedicine: Beauty, utility and limits. Journal of Controlled Release. 2019; 315: 166-85. doi: 10.1016/j.jconrel.2019.10.003
23.    Contera S. Nano Comes to Life: How Nanotechnology Is Transforming Medicine and the Future of Biology. Princeton University Press; 2019.
24.    Freitas RA. Current status of nanomedicine and medical nanorobotics. Journal of Computational and Theoretical Nanoscience 2005; 2(1): 1-25.
25.    Soto C, Recoba R, Barron H, Alvarez C, Favari L. Silymarin increases antioxidant enzymes in alloxan-induced diabetes in rat pancreas. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology.Published online November 1, 2003.
26.    Wang D, Mukhtar A, Humayun M, Wu K, Du Z, Wang S, et al. A Critical Review on Nanowire-Motors: Design, Mechanism and Applications. The Chemical Record. 2022; 22(8): e202200016. doi: 10.1002/tcr.202200016
27.    Mathur D, Medintz IL. The growing development of DNA nanostructures for potential healthcare-related applications. Advanced Healthcare Materials. 2019;8(9):1801546.
28.    Li J, Pumera M. 3D printing of functional microrobots. Chemical Society Reviews 2021; 50(4): 2794-838. doi: 10.1039/D0CS01062F
29.    Keiper A. The Nanotechnology Revolution. The New Atlantis. 2003; 2: 17-34.
30.    Chowdhury R. A review on the application of nanotechnology in Pharmaceutical Science. Published online 2015.
31.    Davies DJ, Vaccaro AR, Morris SM, Herzer N, Schenning AP, Bastiaansen CW. A printable optical time-temperature integrator based on shape memory in a chiral nematic polymer network. Advanced Functional Materials. 2013; 23(21): 2723-7.
32.    Ahmad W, Khan T, Basit I, Imran J. A Comprehensive Review on Targeted Drug Delivery System. AJPR Published online November 22, 2022:335-40. doi: 10.52711/2231-5691.2022.00053





Recomonded Articles:

Author(s): Vinod K.R., Sandhya S

DOI:         Access: Open Access Read More

Author(s): V. S. Parmar, S.C. Shivhare

DOI:         Access: Open Access Read More

Author(s): Domendra Sahu, Shekhar Verma , Ravindra D. Dubey

DOI:         Access: Open Access Read More

Author(s): Hapse S.A., Bhagat B.V., Wagh V.S. , Kadaskar P.T.

DOI:         Access: Open Access Read More

Author(s): Pratik Swarup Das, Puja Saha1, Krishan, Rumpa Das

DOI: :10.5958/0975-4377.2018.00005.8         Access: Open Access Read More

Author(s): Swapnil T. Deshpande, P. S. Vishwe, Rohit D. Shah, Swati S. Korabu, Bhakti R. Chorghe, DG Baheti

DOI:         Access: Open Access Read More

Author(s): Dipti G. Phadtare, Amol R. Pawar, R.B. Saudagar, Govind K.Patil

DOI: 10.5958/0975-4377.2017.00002.7         Access: Open Access Read More

Author(s): Suyash Ingle, Varsha Tegeli, Akshay Javalgikar, Vinod Matole, Lagmanna koli, Avinash Birajdar, Saurabh Nangare, Sagar Adlinge, Swaminath Ramanshetti, Akhil Patil, Yash Kothari, Pandurang Choure, Aaqueeb Mangalgiri, Sneha Ubale, Vaishnavi Dulange, Bhavana habib, Jyoti Mittha

DOI: 10.5958/0975-4377.2021.00013.6         Access: Open Access Read More

Author(s): Yamunappa, Ravi Kumar, Pooja Shetty, Prathibha Suvarna, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00012.4         Access: Open Access Read More

Author(s): Simila Madathil, RaviKumar, Anju Govind, Mercy Mathew, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00013.6         Access: Open Access Read More

Author(s): Dharmendra Kumar Kushwah, Prakash Yashwant Kohle, Bimal Kumar Srivastava, Manoj Parmar ,Dhaval Mehta

DOI:         Access: Open Access Read More

Author(s): Debarupa Dutta, Prithviraj Chakraborty

DOI:         Access: Open Access Read More

Author(s): Kritika Kanoujia, Chandraprabha Dewangan, Ayushi Masih, Dipti Sinha, Divya Oraon, Manisha Jaiswal, Monika Sahu, Ranjeeta Kumari, Sapna Pradhan, Ravi Suman, Rajkishan Dewangan, Roman Banjare, Pradeep Paikra, Mukesh Rawtiya, Mukta Agrawal, Ajazuddin, D. K. Tripathi, Amit Alexander

DOI: 10.5958/0975-4377.2018.00015.0         Access: Open Access Read More

Author(s): Vijay Chudiwal, Sadhana Shahi

DOI: 10.5958/0975-4377.2016.00003.3         Access: Open Access Read More

Author(s): B. Thangabalan, Ch. Sandhya, N. Sunitha, S. Manohar Babu

DOI:         Access: Open Access Read More

Author(s): Debjit Bhowmik, Rishab Bhanot, Darsh Gautam, Parshuram Rai, K.P. Sampath Kumar

DOI: 10.5958/0975-4377.2017.00022.2         Access: Open Access Read More

Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0975-4377 


Recent Articles




Tags