Author(s): M. Venkata Swamy, Samyuktha Metta, A. Ajay Kumar, C. Jagan Mohan Reddy, G. Dharani5, K. Ramya

Email(s): mvenkataswamymlrip@gmail.com

DOI: 10.52711/0975-4377.2023.00001   

Address: M. Venkata Swamy1*, Samyuktha Metta2, A. Ajay Kumar3, C. Jagan Mohan Reddy4, G. Dharani5, K. Ramya6
1Associate Professor, Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
2Associate Professor, Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
3Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
4Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
5Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
6Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 1,     Year - 2023


ABSTRACT:
Multiple Mixes have been proposed to have multitudinous uses including their use for improvement of bioavailability or as a dragged medicine delivery system. But the essential insecurity of this system needs to be overcome before they find implicit operation in medicinals. Multiple mixes are frequently stabilized using a combination of hydrophilic and hydrophobic surfactants. The rate of these surfactants is important in achieving stable multiple mixes. The purpose of the study was to prepare a stable multiple conflation containing a skin anti-aging agent and using paraffin oil emulsion. Vitamin C, was incorporated into the inner waterless phase of water- in- oil emulsion- in- water (w/ o/ w) multiple conflation at a attention of 1. Multiple conflation was prepared by two step system. Stability studies were performed at different accelerated conditions, i.e. 8°C (in refrigerator), 25°C (in roaster), 40°C(in roaster), and 40°C at 75 RH (in stability cabin) for 28 days to prognosticate the stability of phrasings. The ideal of this study was to prepare multiple conflation of Ascorbic acid by two step emulsification using different non-ionic surfactants, Tweens and Agar, and estimate for stability, chance medicine ruse. The study concluded that stable multiple conflation with high ruse effectiveness can be prepared by two step emulsification system using agar- agar primary emulsifier and Tween 80 as secondary emulsifier. F2 formulation is the best formulation than the F1 and F3 formulations based on phase separation and other tests.


Cite this article:
M. Venkata Swamy, Samyuktha Metta, A. Ajay Kumar, C. Jagan Mohan Reddy, G. Dharani5, K. Ramya. Formulation and Characterization of a multiple Emulsion containing Vitamin - C. Research Journal of Pharmaceutical Dosage Forms and Technology.2023; 15(1):1-6. doi: 10.52711/0975-4377.2023.00001

Cite(Electronic):
M. Venkata Swamy, Samyuktha Metta, A. Ajay Kumar, C. Jagan Mohan Reddy, G. Dharani5, K. Ramya. Formulation and Characterization of a multiple Emulsion containing Vitamin - C. Research Journal of Pharmaceutical Dosage Forms and Technology.2023; 15(1):1-6. doi: 10.52711/0975-4377.2023.00001   Available on: https://rjpdft.com/AbstractView.aspx?PID=2023-15-1-1


REFERENCES:
1.    Raynal S, Grossiord JL, Seiller M, Clausse DA. Topical W/O/W multiple emulsion containing several active substances: formulation, characterization and study of release. Controlled Release: Vol. 26, 129-140.
2.    2. Jong-wook Ha And Seung-man Yang., Breakup Of A Multiple Emulsion Drop In A Uniform Electric Field., Journal Of Colloid And Interface Science 213, 92–100 (1999).
3.    Yazan Y and Puisieux F. (1993). Multiple emulsions. Boll Chi Fharmaceutico: Vol. 132, 187–196.
4.    De Luca M, Rocha-Filho P, Grossiord JL, Rabaron A, Vaution C, Seiller M. (1991). Les emulsions multiples, Int J Cosmet Sci: Vol. 13, 1-21.
5.    M.Venkataswamy, Viswanadham Manasa, K. Vanitha, P. Prabhakar, Alluri Ramesh “Formulation and Evaluation of Aqueous Enteric Coated Delayed Release Omeprazole Pellets” Research Journal of Pharmaceutical Dosage Forms and Technology. 8(1): January-March, 2016, (1-4).
6.    M.Venkataswamy, K.Vyshnavi, Madhuri Bhashetty, Namitha Swain, Alluri Ramesh “Evaluation of Prepared   Aspirin Modified Release Tablets with Polymer Isolated from Fresh Mosambi Leaves” Research Journal of Pharmaceutical Dosage Forms and Technology. 9(2): April- June, 2017.
7.    M.Venkataswamy, Arul B, Keerthi Sagar A, Dinesh Mohan S, Vanitha K, Ramesh Alluri “Preparation and Evaluation of a Mucoadhesive Polymer from the Extract of Seeds of Annona squamosa Linn” Asian J. Res. Pharm. Sci. 2017; Vol. 7: Issue 3.
8.    M.Venkataswamy, Chiluveri Sanjuna, Pindrathi Pravalika, Chikoti Sneha Priya, Alluri Ramesh. The Insidious Disease from Insects: Lyme disease. Research Journal of Pharmaceutical Dosage Forms and Technology. 2018; 10(1): 17-22.
9.    M.Venkataswamy, K. Prathyusha, Jaggareddy Gari Manasa Reddy, Alluri Ramesh “Pico technology: Instruments used and Applications in pharmaceutical field” Research Journal of Pharmaceutical Dosage Forms and Technology. 10(1): January- March, 2018, (34-41).
10.    M.Venkataswamy, Jaggareddy gari Manasa Reddy, K. Prathyusha, Alluri Ramesh, “Spreading of Swine flu disease: Past and Present” Research Journal of Pharmaceutical Dosage Forms and Technology.  10(2): April- June, 2018.
11.    M.Venkataswamy, K. Vanitha, Sanam Niharika, Alluri Ramesh. Formulation Development and Evaluation of Mebeverine extended release Pellets. Asian J. Pharm. Tech. 2018; 8 (2):71-77.
12.    M. Venkataswamy, M. Santhoshini, J. P. Priyanka, K. Prathyusha, Jaggareddy Gari Manasareddy and Ramesh Alluri “preparation and evaluation of biphasic bilayered buccal tablet containing ketorolac immediate release layer and domperidone maleate sustained release layer” World Journal of Pharmaceutical Research, Volume 7, Issue 11, 905-949.
13.    M. Venkataswamy, S. Naveen Kumar, B. Ramesh, G. Anantha Ramulu, M. Bharath, K.Sridivya Goud “Preparation And Evaluation of Mucilage from Fresh Leaves of Psidium Guajava” Research Journal of Pharmaceutical Dosage Forms and Technology. 10(3): July- September, 2018.
14.    M.Venkataswamy, Neha Thahaseen, MD Kareemuddin, JP Priyanka, Jaggareddy Gari Manasa Reddy “Formulation And Evaluation of sustained release matrix tablets using drug Cytisine isolated from Fava Beans to quit Smoking” Research Journal of Pharmaceutical Dosage Forms and Technology. 10(3): July- September, 2018.
15.    M.Venkataswamy, Ifath Jabeen, Jawariya Sadaf, Maistry Nishitha Reddy, A.V.Naga Mallika, Mamidi Sushmitha, “drug abuse, addiction, its causes and treatment”, Research Journal of Pharmaceutical Dosage Forms and Technology. 10(3): July- September, 2018.
16.    M.Venkataswamy, Sandhya Mandadi. Formulation And Evaluation Of Metformin Transcutaneous Patches. WJPR. Vol 7, Issue 18, 2018.
17.    M. Venkataswamy, Ch. Sreerekha, Y. Manasa, Boppana Rohini, Kadannagari Surekha, Kilari Sri Kavya “Generic Drugs a Benison to Mankind. RJPDFT, Vol 11(2), 121-125. Apr- June 2019.
18.    M. Venkataswamy, V. Nimitha. Medicinal Plants used for the Treatment of Parkinson's Disease. Research Journal of Pharmaceutical Dosage Forms and Technology. 11(2), Apr- June 2019.
19.    M. Venkataswamy, Ch. Sanjuna. An Arthropod Virus: Chikungunya its Pathophysiology and Herbal Treatment. Research Journal of Pharmaceutical Dosage Forms and Technology. 11(2), Apr- June 2019.
20.    M. Venkataswamy, Sana. Preparation and Evaluation of Ginger Mouth Gargle. Research Journal of Pharmaceutical Dosage Forms and Technology. Vol 11(2), Apr- June 2019.
21.    M. Venkataswamy, K. Prathyusha. Thalassemia. A Blood Disorder, its Cause, Prevention and Management. Research Journal of Pharmaceutical Dosage Forms and Technology. 11(3), Aug- Oct 2019.
22.    M. Venkataswamy, Ch. Sneha. Medicinal Plants used for the Treatment of Bacterial Meningitis. Research Journal of Pharmaceutical Dosage Forms and Technology.  11(3), Aug- Oct 2019.
23.    M. Venkataswamy, Sandhya M. Formulation and Evaluation of Herbal Anti-bacterial gel containing Ethanolic extracts of Rosa Indica and Tagetes Minuta. Research Journal of Pharmaceutical Dosage Forms and Technology.  12(2), Mar- May 2020.
24.    M. Venkataswamy, V. Harshitha. Nanoemulgel: A Process Promising in Drug Delivery System. Research Journal of Pharmaceutical Dosage Forms and Technology. 12(2), Mar- May 2020.
25.    M. Venkataswamy. Formulation and evaluation of microspheres loaded with methotrexate drug. Drug Discovery. 14(34); 2020, 1359-6446.
26.    K. Pravalika, M. Venkata Swamy, J. Shruthi Reddy, K. Anjana Saraswathy, Samyuktha Metta, Bioanalytical Method Developments For Bioanalysis of Drugs, Asian Journal of Pharmaceutical Analysis. 2022, Vol: 12.

Recomonded Articles:

Author(s): Gopal Rao M., M. A. Amutha Gnana Arasi, S. Jayaprakash, M. Arun Kumar, P. Kavitha

DOI:         Access: Open Access Read More

Author(s): V. S. Parmar, S.C. Shivhare

DOI:         Access: Open Access Read More

Author(s): Domendra Sahu, Shekhar Verma , Ravindra D. Dubey

DOI:         Access: Open Access Read More

Author(s): Hapse S.A., Bhagat B.V., Wagh V.S. , Kadaskar P.T.

DOI:         Access: Open Access Read More

Author(s): Pratik Swarup Das, Puja Saha1, Krishan, Rumpa Das

DOI: :10.5958/0975-4377.2018.00005.8         Access: Open Access Read More

Author(s): Swapnil T. Deshpande, P. S. Vishwe, Rohit D. Shah, Swati S. Korabu, Bhakti R. Chorghe, DG Baheti

DOI:         Access: Open Access Read More

Author(s): Dipti G. Phadtare, Amol R. Pawar, R.B. Saudagar, Govind K.Patil

DOI: 10.5958/0975-4377.2017.00002.7         Access: Open Access Read More

Author(s): Yamunappa, Ravi Kumar, Pooja Shetty, Prathibha Suvarna, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00012.4         Access: Open Access Read More

Author(s): Simila Madathil, RaviKumar, Anju Govind, Mercy Mathew, Narayana Swamy VB

DOI: 10.5958/0975-4377.2016.00013.6         Access: Open Access Read More

Author(s): Soham Shukla, Vikram Pandya, Praful Bhardia, Nitin Jonwal, Shashank Mishra, Deepak Bhatt, Deependra Jain

DOI:         Access: Open Access Read More

Author(s): Dharmendra Kumar Kushwah, Prakash Yashwant Kohle, Bimal Kumar Srivastava, Manoj Parmar ,Dhaval Mehta

DOI:         Access: Open Access Read More

Author(s): Chirag A. Patel, Priyal R. Patel, Dhrubo Jyoti Sen,Jayvadan K. Patel

DOI:         Access: Open Access Read More

Author(s): Kritika Kanoujia, Chandraprabha Dewangan, Ayushi Masih, Dipti Sinha, Divya Oraon, Manisha Jaiswal, Monika Sahu, Ranjeeta Kumari, Sapna Pradhan, Ravi Suman, Rajkishan Dewangan, Roman Banjare, Pradeep Paikra, Mukesh Rawtiya, Mukta Agrawal, Ajazuddin, D. K. Tripathi, Amit Alexander

DOI: 10.5958/0975-4377.2018.00015.0         Access: Open Access Read More

Author(s): Vidya N. Dange, Shubhangi J. Shid, Sagar B. Patil, Ganesh B. Vambhurkar, Mangesh A. Bhutkar

DOI: 10.5958/0975-4377.2019.00010.7         Access: Open Access Read More

Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0975-4377 


Recent Articles




Tags