Author(s):
M. Venkata Swamy, Samyuktha Metta, A. Ajay Kumar, C. Jagan Mohan Reddy, G. Dharani5, K. Ramya
Email(s):
mvenkataswamymlrip@gmail.com
DOI:
10.52711/0975-4377.2023.00001 
Address:
M. Venkata Swamy1*, Samyuktha Metta2, A. Ajay Kumar3, C. Jagan Mohan Reddy4, G. Dharani5, K. Ramya6
1Associate Professor, Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
2Associate Professor, Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
3Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
4Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
5Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
6Department of Pharmaceutics, Marri Laxman Reddy Institute of Pharmacy, Hyderabad, Telangana-500043, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 1,
Year - 2023
ABSTRACT:
Multiple Mixes have been proposed to have multitudinous uses including their use for improvement of bioavailability or as a dragged medicine delivery system. But the essential insecurity of this system needs to be overcome before they find implicit operation in medicinals. Multiple mixes are frequently stabilized using a combination of hydrophilic and hydrophobic surfactants. The rate of these surfactants is important in achieving stable multiple mixes. The purpose of the study was to prepare a stable multiple conflation containing a skin anti-aging agent and using paraffin oil emulsion. Vitamin C, was incorporated into the inner waterless phase of water- in- oil emulsion- in- water (w/ o/ w) multiple conflation at a attention of 1. Multiple conflation was prepared by two step system. Stability studies were performed at different accelerated conditions, i.e. 8°C (in refrigerator), 25°C (in roaster), 40°C(in roaster), and 40°C at 75 RH (in stability cabin) for 28 days to prognosticate the stability of phrasings. The ideal of this study was to prepare multiple conflation of Ascorbic acid by two step emulsification using different non-ionic surfactants, Tweens and Agar, and estimate for stability, chance medicine ruse. The study concluded that stable multiple conflation with high ruse effectiveness can be prepared by two step emulsification system using agar- agar primary emulsifier and Tween 80 as secondary emulsifier. F2 formulation is the best formulation than the F1 and F3 formulations based on phase separation and other tests.
Cite this article:
M. Venkata Swamy, Samyuktha Metta, A. Ajay Kumar, C. Jagan Mohan Reddy, G. Dharani5, K. Ramya. Formulation and Characterization of a multiple Emulsion containing Vitamin - C. Research Journal of Pharmaceutical Dosage Forms and Technology.2023; 15(1):1-6. doi: 10.52711/0975-4377.2023.00001
Cite(Electronic):
M. Venkata Swamy, Samyuktha Metta, A. Ajay Kumar, C. Jagan Mohan Reddy, G. Dharani5, K. Ramya. Formulation and Characterization of a multiple Emulsion containing Vitamin - C. Research Journal of Pharmaceutical Dosage Forms and Technology.2023; 15(1):1-6. doi: 10.52711/0975-4377.2023.00001 Available on: https://rjpdft.com/AbstractView.aspx?PID=2023-15-1-1
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18. M. Venkataswamy, V. Nimitha. Medicinal Plants used for the Treatment of Parkinson's Disease. Research Journal of Pharmaceutical Dosage Forms and Technology. 11(2), Apr- June 2019.
19. M. Venkataswamy, Ch. Sanjuna. An Arthropod Virus: Chikungunya its Pathophysiology and Herbal Treatment. Research Journal of Pharmaceutical Dosage Forms and Technology. 11(2), Apr- June 2019.
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22. M. Venkataswamy, Ch. Sneha. Medicinal Plants used for the Treatment of Bacterial Meningitis. Research Journal of Pharmaceutical Dosage Forms and Technology. 11(3), Aug- Oct 2019.
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