Chronic diseases such as cancer, diabetes, neurodegenerative and cardiovascular diseases are characterized by an enhanced state of oxidative stress, which may result from the overproduction of reactive species and/or a decrease in antioxidant defenses. The search for new chemical entities with antioxidant profile is still thus an emerging field on ongoing interest. Psidium guajava leaves have traditionally been used to manage several diseases such as rheumatism, diarrhea, diabetes mellitus, and cough. The results of the free radical scavenging activity of the DPPH radical assay method for antioxidant activity have shown that the Psidium guajava extract exhibits significant scavenging activity.
Cite this article:
Akshay R. Yadav, Shrinivas K. Mohite, Manisha D. Rajput, Vaibhav S. Suryawanshi, Rushikesh M. Birajdar, Mayuri V. Patil. Antioxidant Activity of Psidium guajava Leaf Extracts. Res. J. Pharma. Dosage Forms and Tech.2020; 12(3):159-161. doi: 10.5958/0975-4377.2020.00027.0
Akshay R. Yadav, Shrinivas K. Mohite, Manisha D. Rajput, Vaibhav S. Suryawanshi, Rushikesh M. Birajdar, Mayuri V. Patil. Antioxidant Activity of Psidium guajava Leaf Extracts. Res. J. Pharma. Dosage Forms and Tech.2020; 12(3):159-161. doi: 10.5958/0975-4377.2020.00027.0 Available on: https://rjpdft.com/AbstractView.aspx?PID=2020-12-3-4
1. Panchawat S, Rathore KS, Sisodia SS. A review on herbal antioxidants. International Journal of Pharm Tech Research. 2010; 2(1): 232-239.
2. B. R. Panda, S. R. Mohanta, A. K. Manna, S. Si. Invitro antioxidant activity on the aerial parts of Cocculus hirsutus Diels. J Adv Pharm Res. 2011; 2(1): 18-23.
3. Udayakumar R, Kasthurirengan S, Vasudevan A, Mariashibu TS, Rayan JJ, Choi CW, Ganapathi A, Kim SC. Antioxidant effect of dietary supplement Withania somnifera L. reduce blood glucose levels in alloxan-induced diabetic rats. Plant Foods Hum Nutr. 2010; 65: 91-98.
4. Kosanic M, Rankovic B, Stanojkovic T, Rancic A, Manojlovoic N. Cladonia lichens and their major metabolites as possible natural antioxidant, antimicrobial and anticancer agents. LWT Food Sci. Technol. 2014; 59: 518–525.
5. Papadopoulou P, Tzakou O, Vagias C, Kefalas P, Roussis V. Beta-orcinol metabolites from the lichen Hypotrachyna revoluta. Molecules. 2007; 12: 997–1005.
6. Jayaprakasha G.K, Rao L J. Phenolic constituents from the lichen Parmotrema stuppeum (Nyl.) Hale and their antioxidant activity. Z. Naturforsch. C. 2000; 55: 1018–1022.
7. Odabasoglu F, Yildirim O, Aygun H, Halici Z, Halici M, Erdogan F, Cadirci E, Cakir, A, Okumus Z, Aksakal B. Diffractaic acid, a novel proapoptotic agent, induces with olive oil both apoptosis and antioxidative systems in Ti-implanted rabbits. Eur. J. Pharmacol. 2012; 674: 171–178.
8. Kosanić M, Manojlović N, Janković S, Stanojković T, Ranković B. Evernia prunastri and Pseudoevernia furfuraceae lichens and their major metabolites as antioxidant, antimicrobial and anticancer agents. Food Chem. Toxicol. 2013; 53: 112–118.
9. Ghosh P, Mandal A, Chakraborty P. Triterpenoids from Psidium guajava with biocidal activity. Indian J Pharm Sci. 2010; 72(4): 504-507.
10. Qadan F, Thewaini AJ, Ali DA, Afifi R, Elkhawad A, Matalka KZ. The antimicrobial activities of Psidium guajava and Juglans regia leaf extracts to acne-developing organisms. Am J ChinMed. 2005; 33(2): 197-204.
11. Chah KF, Eze CA, Emuelosi CE, Esimone CO. Antibacterial and wound healing properties of methanolic extracts of some Nigerian medicinal plants. J Ethnopharmacol. 2006; 104(2):164-167.
12. Deo A, Shastri NV. Purification and characterization of polygalacturonase-inhibitory proteins from Psidium guajava Linn. (guava) fruit. Plant Sci. 2003; 164: 147-156.
13. Rahim N, Gomes D, Watanabe H. Antibacterial activity of Psidium guajava leaf and bark against multidrug-resistant Vibrio cholerae: implication for cholera control. Jpn J Infect Dis. 2010; 63(4): 271-274.
14. Anas K, Jayasree P, Vijayakumar T, Kumar M. In vitro antibacterial activity of Psidium guajava Linn. leaf extract on clinical isolates of multidrug resistant Staphylococcus aureus. Indian J Exp Biol. 2008; 46(1): 41-46.
15. Yadav A, Mohite S. Screening of In-vitro anti-inflammatory and Antibacterial assay of Malvastrum Coromandelianum. International Journal of Pharma Sciences and Research. 2020; 11(4): 68-70.
16. Anyinam C. Ecology and ethnomedicine: Exploring links between current environmental crisis and indigenous medical practices. Soc. Sci. Med. 1995; 40: 321–329.
17. Patwardhan B, Warude D, Pushpangadan P, Bhatt N. Ayurveda and traditional Chinese medicine: A comparative overview. Evid. Based Complement. Altern. Med. 2005; 2: 465–473.
18. Gutierrez R, Mitchell S, Solis RV. Psidium guajava: A review of its traditional uses, phytochemistry and pharmacology. J. Ethnopharmacol. 2008; 117: 1–27.
19. Shruthi SD, Roshan A, Sharma S, Sunita S. A review on the medicinal plant Psidium guajava Linn. (Myrtaceae). J. Drug Deliv. Ther. 2013; 3: 162–168.
20. Vishwananthan B, Gurupadayya B, Sairam K, Inturi B. Design, synthesis, In vitro antioxidant and in vivo anti-inflammatory activities of novel oxadiazole derivatives. Int J Pharm Pharm Sci. 2014; 6(9): 514-520.
21. Adesegun S, Fajana A, Orabueze C, Coker H. Evaluation of antioxidant properties of phaulopsis fascisepala C.B.Cl. (Acanthaceae). Evid Based Complement Alternat Med. 2009; 6: 227‑231.