Volume No. :   6

Issue No. :  1

Year :  2014

ISSN Print :  0975-234X

ISSN Online :  0975-4377


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Synthesis of Chalcones and Evaluation of Their Anti-Microbial Activity

Address:   P. Parveen1*, P. Usha1, V. Vasu Naik1, Sk. Shaheda Sultana1, M. Gayatri Ramya2
1Hindu College of Pharmacy, Amaravathi Road, Guntur-522002
2University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Guntur-500510
*Corresponding Author

Chalcones are main precursor for biosynthesis of flavonoids which are frequent components of human diet. Recent studies on biological evaluation of chalcones revealed some Anticancer, Anti inflammatory, Anti mitotic, Anti tubercular, Cardiovascular, cell differenciation inducing, nitric oxide regulation modulatory and hyperglycaemic activities. This present research includes synthesis of varies chalcones from 5-acetyl salicylamide and evaluation of their anti microbial activity. Objective 1. To synthesize chalcones using different catalyst solid NaOH. 2. Characterize chalcones using TLC, NMR, MASS and IR spectrometry. 3. To evaluate the anti-microbial activity .
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P. Parveen, P. Usha, V. Vasu Naik, Sk. Shaheda Sultana, M. Gayatri Ramya. Synthesis of Chalcones and Evaluation of Their Anti-Microbial Activity. Res. J. Pharm. Dosage Form. & Tech. 6(1): Jan.-Mar. 2014; Page 26-32.
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