Chronopharmaceutics: A Clinically Relevant Approach to Drug Delivery

Gaurav Tiwari; Awani K Rai; Vachaspati Dubey; Anil Sharma; Pranay Wal; Ankita Wal

Research Journal of Pharmaceutical Dosage Forms and Technology

ISSN

0975-4377 (Online)
0975-234X (Print)

Submit Article

Chronopharmaceutics: A Clinically Relevant Approach to Drug Delivery

Author(s): Gaurav Tiwari, Awani K Rai, Vachaspati Dubey, Anil Sharma, Pranay Wal, Ankita Wal

Email(s): tiwari_mpharm@rediffmail.com

DOI: Not Available

Address: Gaurav Tiwari2*, Awani K Rai1, Vachaspati Dubey1, Anil Sharma3, Pranay Wal1 and Ankita Wal1
1Department of Pharmaceutics, Pranveer Singh Institute of Technology, Kalpi Road, Bhauti Kanpur 208020, (Uttar Pradesh), India
2Jaipur National University, Jagatpura, Jaipur, Rajasthan
3Suresh Gyan Vihar University, Jaipur, Rajasthan
*Corresponding Author:

Published In: Volume - 2, Issue - 2, Year - 2010

View HTML

View PDF

ABSTRACT:
Chronopharmaceutics covers the fundamentals of the various aspects of chronopharmaceutics in the fields of chronobiology, chronogenetics, chronophysiology, chronopathology, chronopharmacology, chronotherapeutics, chronotoxicology and chronobiotics, and chronopharmaceutical drug delivery research. It discusses different and specific controlled-release systems that are triggered by electrics, diffusion, and chemical-activation and concludes with a description of the regulatory issues along with formulation and manufacturing.Due to advances in chronobiology, chronopharmacology, and global market constraints, the traditional goal of pharmaceutics (e.g. design drug delivery systems with a constant drug release rate) is becoming obsolete. However, the major bottleneck in the development of drug delivery systems that match the circadian rhythm (chronopharmaceutical drug delivery systems: ChrDDS) may be the availability of appropriate technology. The last decade has witnessed the emergence of ChrDDS against several diseases. The increasing research interest surrounding ChrDDS may lead to the creation of a new subdiscipline in pharmaceutics known as chronopharmaceutics. This review introduces the concept of chronopharmaceutics, addresses theoretical/formal approaches to this sub-discipline, underscores potential disease-targets, revisits existing technologies and examples of ChrDDS. Future development in chronopharmaceutics may be made at the interface of other emerging disciplines such as system biology and nanomedicine. Such novel and more biological approaches to drug delivery may lead to safer and more efficient disease therapy in the future.

Keywords:

Cite this article:
Gaurav Tiwari, Awani K Rai, Vachaspati Dubey, Anil Sharma, Pranay Wal, Ankita Wal. Chronopharmaceutics: A Clinically Relevant Approach to Drug Delivery. Research J. Pharma. Dosage Forms and Tech. 2010; 2(2):139-145.

Cite(Electronic):
Gaurav Tiwari, Awani K Rai, Vachaspati Dubey, Anil Sharma, Pranay Wal, Ankita Wal. Chronopharmaceutics: A Clinically Relevant Approach to Drug Delivery. Research J. Pharma. Dosage Forms and Tech. 2010; 2(2):139-145. Available on: https://rjpdft.com/AbstractView.aspx?PID=2010-2-2-5

Recomonded Articles:

Pharmaceutical Suspensions: Pharmacist has the Very Best Possible Formulation for the Job at Hand.

Author(s): Praneta Desale

DOI: Access: Open Access Read More

A Brief Review on Intra-Uterine Drug Delivery Systems

Author(s): Suyash Ingle, Varsha Tegeli, Akshay Javalgikar, Vinod Matole, Lagmanna koli, Avinash Birajdar, Saurabh Nangare, Sagar Adlinge, Swaminath Ramanshetti, Akhil Patil, Yash Kothari, Pandurang Choure, Aaqueeb Mangalgiri, Sneha Ubale, Vaishnavi Dulange, Bhavana habib, Jyoti Mittha

DOI: 10.5958/0975-4377.2021.00013.6 Access: Open Access Read More

Formulation and Evaluation of Tolperisone Hydrochloride Sustained Release Tablet

Author(s): Domendra Sahu, Shekhar Verma , Ravindra D. Dubey

DOI: Access: Open Access Read More

Transdermal Drug Delivery System of Antidiabetic Drugs: A Review

Author(s): Swapnil T. Deshpande, P. S. Vishwe, Rohit D. Shah, Swati S. Korabu, Bhakti R. Chorghe, DG Baheti

DOI: Access: Open Access Read More

Formulation and Evaluation of Solid Lipid Nanoparticle Based Transdermal Drug Delivery System for Alzheimer’s Disease

Author(s): Pramod Salve, Suvarna Pise, Nikhil Bali

DOI: 10.5958/0975-4377.2016.00011.2 Access: Open Access Read More

Self Microemulsifying Drug Delivery System (SMEDDS): A Novel Approach to Improve the Therapeutic Efficacy of Orally Administered Drug

Author(s): Kritika Kanoujia, Chandraprabha Dewangan, Ayushi Masih, Dipti Sinha, Divya Oraon, Manisha Jaiswal, Monika Sahu, Ranjeeta Kumari, Sapna Pradhan, Ravi Suman, Rajkishan Dewangan, Roman Banjare, Pradeep Paikra, Mukesh Rawtiya, Mukta Agrawal, Ajazuddin, D. K. Tripathi, Amit Alexander

DOI: 10.5958/0975-4377.2018.00015.0 Access: Open Access Read More

Formulation Development and Evaluation of Sodium Valproate and Valproic acid Extended Release Tablets

Author(s): K. Vanitha, Prasanna Kumar Desu

DOI: 10.5958/0975-4377.2019.00012.0 Access: Open Access Read More

Patent Perspective of Advanced Gastroretentive Drug Delivery Systems

Author(s): Vijay Chudiwal, Sadhana Shahi

DOI: 10.5958/0975-4377.2016.00003.3 Access: Open Access Read More

Fast Dissolving Tablets-An Updated Review

Author(s): Ashok Thulluru, K. Saravanakumar, Ch. S. Phani Kumar, Nawaz Mahammed, D. Sreeja, G. Bhuvanesh, N. Vamsi Chowdary, Nayeema Khowser Shaik

DOI: 10.5958/0975-4377.2019.00049.1 Access: Open Access Read More

Formulation Development of Ketoconazole Ophthalmic Formulation

Author(s): Varsha R. Sandhan, S.B. Gondkar, R. B. Saudagar

DOI: Access: Open Access Read More

Formulation and Evaluation of Lomefloxacin Microspheres

Author(s): Swati S Talokar, Rohan R Vakhariya

DOI: 10.5958/0975-4377.2017.00001.5 Access: Open Access Read More

Preparation and Evaluation of Pantoprazole sodium floating microspheres

Author(s): Doppalapudi Sandeep, A. P. Pratyusha, G. Sudheshna, K. Lakshmi prasanna, P. Sreekanth

DOI: Access: Open Access Read More

Microemulsion: A Current Review

Author(s): Sushant R. Jagtap, D.G Phadtare, R.B. Saudagar

DOI: 10.5958/0975-4377.2016.00021.5 Access: Open Access Read More

Formulation Development and Evaluation of Buccal Patches of Aceclofenac for Gingivitis

Author(s): Puja Saha, Pratik Swarup Das

DOI: 10.5958/0975-4377.2017.00026.X Access: Open Access Read More

Nanosponges - Overview

Author(s): Rajkumar Prasad Yadav, F. R. Sheeba

DOI: 10.52711/0975-4377.2021.00023 Access: Open Access Read More

A Review on Solid Lipid Nanoparticle

Author(s): Patil Amol M, Todkar Rohit R, Gumte Dipak S, S.K. Mohite, C.S. Magdum

DOI: 10.5958/0975-4377.2016.00030.6 Access: Open Access Read More

Role of Penetration Enhancers in Transdermal Drug Delivery System

Author(s): Saikumar Y., Saikishore V., Pavani K., Sairam D.T., Sindhura A.

DOI: Access: Open Access Read More

Fast Dissolving Tablets- A Review and Recent Advances in Manufacturing Technologies

Author(s): K Sonu Sharma, Rashmi Sharma, G Vidya Sagar

DOI: Access: Open Access Read More

Enzyme Immobilization: A Bridge of Understanding between Biotechnology and Pharmacy

Author(s): Nisha Nair, Amrita Thakur, Mukta Agrawal, Juhi Thakur,Shubhangi Gupta, Bharti Sahu, Devendra kumar, Indu Rai, Jaya Sonkar, Kalyani Sahu, Kuldeep, Kailash Kumar, Muktanand, Nidhi Kaushik, Omkar Sahu, Somsunder Sahu, Umesh Kumar, D. K. Tripathi, Ajazuddin, Amit Alexander

DOI: 10.5958/0975-4377.2018.00017.4 Access: Open Access Read More

Polymers used in Drug Delivery System: An Overview

Author(s): Swapnali A. Mohite, R. R. Vakhariya, S. K. Mohite, C. S. Magdum

DOI: 10.5958/0975-4377.2019.00017.X Access: Open Access Read More

Research Journal of Pharmaceutical Dosage Forms and Technology (RJPDFT) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. ...... Read more >>>

RNI: Not Available
DOI: 10.5958/0975-4377