Author(s):
Mayur Chavan, Rushikesh Bachhav, Mayur Bhamare, Yogesh Sharma, Khemchand Surana, Shivraj Jadhav, Sunil Mahajan
Email(s):
mayurchavan62204@gmail.com
DOI:
10.52711/0975-4377.2025.00003 
Address:
Mayur Chavan1, Rushikesh Bachhav2, Mayur Bhamare2, Yogesh Sharma2, Khemchand Surana2, Shivraj Jadhav2, Sunil Mahajan2
1Department of Pharmaceutics, Divine College of Pharmacy, Satana, Nashik, Affiliated by Savitribai Phule Pune University, Maharashtra 423301.
2Department of Pharmaceutical Quality Assurance, Divine College of Pharmacy, Satana, Nashik, Affiliated by Savitribai Phule Pune University, Maharashtra 423301.
*Corresponding Author
Published In:
Volume - 17,
Issue - 1,
Year - 2025
ABSTRACT:
Shatdhaut Ghrita (SDG), an Ayurvedic preparation of clarified butter (ghee) washed 100 times with water, has been traditionally used for its therapeutic properties in skin care. This review evaluates its efficacy and potential as a base in moisturizing cream formulations. The literature highlights SDG's unique physicochemical properties, including enhanced bioavailability, stability, and penetration potential due to nanoscale particle size and emulsion formation. SDG's composition—rich in short- and medium-chain fatty acids, antioxidants, and anti-inflammatory compounds—provides significant hydration, skin barrier repair, and wound healing benefits. The review also explores SDG’s compatibility with other excipients, showing its capacity to form stable emulsions and enhance the delivery of active pharmaceutical ingredients. Studies confirm its role in reducing transepidermal water loss (TEWL), alleviating conditions like eczema, psoriasis, and dry skin. Challenges in formulating with SDG, such as odor masking and standardization, are addressed with modern techniques. In conclusion, Shatdhaut Ghrita demonstrates excellent potential as a natural and effective base for moisturizing creams, warranting further clinical and formulation studies to standardize its use in modern cosmeceuticals.
Cite this article:
Mayur Chavan, Rushikesh Bachhav, Mayur Bhamare, Yogesh Sharma, Khemchand Surana, Shivraj Jadhav, Sunil Mahajan. Detailed Review of Shatdhaut Ghrita as a Base in Moisturizing Cream. Research Journal of Pharmaceutical Dosage Forms and Technology. 2025; 17(1):19-5. doi: 10.52711/0975-4377.2025.00003
Cite(Electronic):
Mayur Chavan, Rushikesh Bachhav, Mayur Bhamare, Yogesh Sharma, Khemchand Surana, Shivraj Jadhav, Sunil Mahajan. Detailed Review of Shatdhaut Ghrita as a Base in Moisturizing Cream. Research Journal of Pharmaceutical Dosage Forms and Technology. 2025; 17(1):19-5. doi: 10.52711/0975-4377.2025.00003 Available on: https://rjpdft.com/AbstractView.aspx?PID=2025-17-1-3
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