Formulation and Evaluation of Lipid Microspheres of Ketoprofen

Preethi Sudheer; Ramesh Babu H.V; Soosamma John

Research Journal of Pharmaceutical Dosage Forms and Technology

ISSN

0975-4377 (Online)
0975-234X (Print)

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Formulation and Evaluation of Lipid Microspheres of Ketoprofen

Author(s): Preethi Sudheer, Ramesh Babu H.V, Soosamma John

Email(s): preethiksudheer@rediffmail.com

DOI: Not Available

Address: Preethi Sudheer*, Ramesh Babu H.V and Soosamma John
East Point College of Pharmacy, Bidarahalli, Virgo Nagar Post, Bangalore, 560049.
*Corresponding Author:

Published In: Volume - 2, Issue - 5, Year - 2010

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ABSTRACT:
Lipid microspheres of ketoprofen was prepared by emulsification method using waxes such as bees wax, carnauba wax and cetosteryl alcohol. These microspheres were evaluated for in-vitro dissolution studies, thin layer chromatography, scanning electron microscopy and particle size analysis. Lipid microspheres were studied for diffusion characteristics using cellophane membrane and permeation characteristics through excised rat abdominal skin. Lipid microspheres were found to increase the rate of permeation of poorly absorbable ketoprofen, so they may be used as a potential carrier in increasing the rate of absorption in case of topical delivery of drugs.

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Cite this article:
Preethi Sudheer, Ramesh Babu H.V, Soosamma John. Formulation and Evaluation of Lipid Microspheres of Ketoprofen. Research J. Pharma. Dosage Forms and Tech. 2010; 2(5): 340-343 .

Cite(Electronic):
Preethi Sudheer, Ramesh Babu H.V, Soosamma John. Formulation and Evaluation of Lipid Microspheres of Ketoprofen. Research J. Pharma. Dosage Forms and Tech. 2010; 2(5): 340-343 . Available on: https://rjpdft.com/AbstractView.aspx?PID=2010-2-5-5

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DOI: 10.5958/0975-4377