Volume No. :   11

Issue No. :  4

Year :  2019

ISSN Print :  0975-234X

ISSN Online :  0975-4377


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Fast Dissolving Tablets-An Updated Review



Address:   Ashok Thulluru*1, K. Saravanakumar2, Ch. S. Phani Kumar3, Nawaz Mahammed2, D. Sreeja2, G. Bhuvanesh2, N. Vamsi Chowdary2, Nayeema Khowser Shaik2
1Dept. of Pharmaceutics & Q.A. Shri Vishnu College of Pharmacy (Autonomous), Vishnupur, Bhimavaram-534 202, W.G.(Dist.)
A.P., India.
2Dept. of Pharmaceutics, Sree Vidyanikethan College of Pharmacy, A. Rangampet, Tirupati-517102, Chittoor (Dist.), A.P., India.
3Dept. of Pharmaceutics, Adarsa College of Pharmacy, G. Kothapalli-533285, Gokavaram (Md.), E. G. (Dist.), A.P. India.
*Corresponding Author
DOI No: 10.5958/0975-4377.2019.00049.1

ABSTRACT:
Fast dissolving tablets (FDTs) is one of the most widely accepted and popular dosage form, especially for paediatric and geriatric patients. Conventional solid dosage forms like tablets and capsules are facing the problems like difficulty in swallowing (dysphasia), resulting in many incidences of non-compliance. FDTs have benefits such as accurate dosing, easy portability, and ease of manufacturing; good physical and chemical stability. FDTs are designed in such a way that, they are dissolved rapidly in the saliva less than 60 sec. Direct compression method is preferred among all the other conventional methods of their preparation. Compared to the conventional tablets the amount of drug that is subject to first pass metabolism is reduced, thereby increase the bioavailability of the drug. Various patented technologies and marketed FDTs are updated in this review. Due to its potential market and advantages, many drugs (e.g. neuroleptics, CVS, analgesics, antihistamines and erectile dysfunction) will be developed as FDTs in the future.
KEYWORDS:
Fast dissolving tablets (FDTs), dysphasia, non-compliance, direct compression, bioavailability, patented technologies.
Cite:
Ashok Thulluru, K. Saravanakumar, Ch. S. Phani Kumar, Nawaz Mahammed, D. Sreeja, G. Bhuvanesh, N. Vamsi Chowdary, Nayeema Khowser Shaik. Fast Dissolving Tablets-An Updated Review. Res. J. Pharma. Dosage Forms and Tech.2019; 11(4):296-303.
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