Volume No. :   11

Issue No. :  2

Year :  2019

ISSN Print :  0975-234X

ISSN Online :  0975-4377


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Medicinal Plants used for the Treatment of Parkinson’s Disease



Address:   V. Nimitha*, M. Venkataswamy*, P. Vaishnavi, M. Sai Manisha, V. Swathi, R. Saritha
Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak District– 502313, Telangana, India
*Corresponding Author
DOI No: 10.5958/0975-4377.2019.00022.3

ABSTRACT:
Parkinsonism is single of the regular neurodegenerative diseases, which is distinguished through a discriminating and advancement deterioration of dopaminergic neurons, root a sequence of sign which might finally persuade automatic cell demise, although the etiology of parkinsonism ruins unknown, current studies have optional that oxidative stress(OS), generate apoptosis which results in mitochondrial defects, neuroinflammation may also play important roles in its pathogenesis.Various agents as 6-Hydroxydopomine(6-OHDA), 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Rotenone a neurotoxin commonly and many more are used in models of PD, induces selective catecholaminergic cell death, mediated by reactive oxygen species(ROS) and mitochondrial defects.
KEYWORDS:
Parkinson’s, Disease, Medicinal Plants, Rotenone.
Cite:
V. Nimitha, M. Venkataswamy, P. Vaishnavi, M. Sai Manisha, V. Swathi, R. Saritha. Medicinal Plants used for the Treatment of Parkinson’s Disease. Res. J. Pharma. Dosage Forms and Tech.2019; 11(2):134-136.
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