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Research Journal of Pharmaceutical Dosage Forms and Technology
ISSN: 0975-4377(Online), 0975-234X(Print)
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Extended Release Drug Delivery-An Effective Way of Novel Drug Delivery System
K.P. Sampath Kumar
Debjit Bhowmik1*, Rishab Bhanot2, K.P. Sampath Kumar3
1Himachal Pharmacy College, Nalagarh, Himachal Pradesh
2Himachal Institute of Pharmaceutical Education and Research, Nadaun, Hamirpur, H.P.
3Department of Pharmacy, Coimbatore Government Medical College, Coimbatore
Extended release means the pill is formulated so that the drug is released slowly over time. This has the advantage of taking pills less often. Also means that there may be fewer side effects as the levels of the of drug in the body are more consistent in extended release formulations. Extended-release dosage consists of sustained-release and controlled-release dosage. Sustained release maintains drug release over a sustained period but not at a constant rate. Controlled-release maintains drug release over a sustained period at a nearly constant rate. The basic goal of sustained release is provide promising way to decrease the side effect of drug by preventing the fluctuation of the therapeutic concentration of the drug in the body and increase patient compliance by reducing frequency of dose. This article contains the basic information regarding sustained-release formulation and also the different types of the same. Drug products designed to reduce the frequency of dosing by modifying the rate of drug absorption. For extended release formulations the polymers need to have certain characteristics to control and maintain the rigidity of the matrix over a prolonged period. Extended release drug delivery technology can provide: Smooth plasma levels of drug over longer periods of time, Reduce dosing frequency and Improve the patient compliance.
Extended Release, Drug Delivery, Novel Drug Delivery System
Debjit Bhowmik, Rishab Bhanot, K.P. Sampath Kumar. Extended Release Drug Delivery-An Effective Way of Novel Drug Delivery System. Res. J. Pharm. Dosage Form. & Tech. 2018; 10(4): 233-244.
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