Volume No. :   8

Issue No. :  4

Year :  2016

ISSN Print :  0975-234X

ISSN Online :  0975-4377


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UV Spectrophotometric Method Development and Validation of Lornoxicam Loaded Solid SMEDDS



Address:   Pankaj P. Pawar1*, Dipti G. Phadtare2
1Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik.
2Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik.
*Corresponding Author
DOI No: 10.5958/0975-4377.2016.00037.9

ABSTRACT:
Analytical methods development and validation play important roles in the discovery, development, and manufacture of pharmaceuticals. Simple, precise and accurate UV spectroscopic method has been developed and validated for estimation of Lornoxicam loaded solid SMEDDS. UV spectroscopic method which is based on measurement of absorption of UV light, the spectra of Lornoxicam SMEDDS in 0.1N NaOHshowed maximum wavelength at 375nm and calibration curve were plotted over the concentrations ranging from 5-50ug/ml of Lornoxicam SMEDDS with correlation coefficient 0.999 validation was performed as per ICH Q2 (R1) guidelines for linearity, accuracy, precision and recovery. The proposed method was validated.
KEYWORDS:
Lornoxicam, 0.1N NaOH, Spectrophotometer and Validation.
Cite:
Pankaj P. Pawar, Dipti G. Phadtare. UV Spectrophotometric Method Development and Validation of Lornoxicam Loaded Solid SMEDDS. Res. J. Pharm. Dosage Form. & Tech. 2016; 8(4): 269-272.
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