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Research Journal of Pharmaceutical Dosage Forms and Technology
ISSN: 0975-4377(Online), 0975-234X(Print)
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UV Spectrophotometric Method Development and Validation of Lornoxicam Loaded Solid SMEDDS
Pankaj P. Pawar
Dipti G. Phadtare
Email ID Not Available
Pankaj P. Pawar1*, Dipti G. Phadtare2
1Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik.
2Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik.
Analytical methods development and validation play important roles in the discovery, development, and manufacture of pharmaceuticals. Simple, precise and accurate UV spectroscopic method has been developed and validated for estimation of Lornoxicam loaded solid SMEDDS. UV spectroscopic method which is based on measurement of absorption of UV light, the spectra of Lornoxicam SMEDDS in 0.1N NaOHshowed maximum wavelength at 375nm and calibration curve were plotted over the concentrations ranging from 5-50ug/ml of Lornoxicam SMEDDS with correlation coefficient 0.999 validation was performed as per ICH Q2 (R1) guidelines for linearity, accuracy, precision and recovery. The proposed method was validated.
Lornoxicam, 0.1N NaOH, Spectrophotometer and Validation.
Pankaj P. Pawar, Dipti G. Phadtare. UV Spectrophotometric Method Development and Validation of Lornoxicam Loaded Solid SMEDDS. Res. J. Pharm. Dosage Form. & Tech. 2016; 8(4): 269-272.
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