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Research Journal of Pharmaceutical Dosage Forms and Technology
ISSN: 0975-4377(Online), 0975-234X(Print)
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Glimpse of Floating Drug Delivery in Pharmaceutical Formulations: A Review
Gunjan L. Zope
A. B. Darekar
R. B. Saudagar
Gunjan L. Zope1*, A. B. Darekar1, R. B. Saudagar2
1Department of Pharmaceutics, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India.
2Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India.
In recent years the novel technology of floating drug delivery system formulations are designed for the new drugs for oral targeted drug delivery. The drugs are delivered by conventional dosage forms are having very short residence time, but the drugs which are act in stomach are have more residence time. The floating drug delivery systems are of particular interest for drugs drugs that are locally active and narrow absorption window in stomach. System which are retained in the stomach for a longer period of time and there by improve the bioavailability of drugs. In this review the various advantages are given which are very important for controlled drug delivery system. Floating drug delivery system have a bulk density less than gastric fluids. When the system floats on gastric contents the drug is released slowly at the desire rate from system. The polymers are suitable for floating drug delivery system are covered in this review.
Floating Drug Delivery System, Mechanism and types of FDDS, Evaluation of FDDS
Gunjan L. Zope, A. B. Darekar, R. B. Saudagar. Glimpse of Floating Drug Delivery in Pharmaceutical Formulations: A Review. Res. J. Pharm. Dosage Form. and Tech. 2016; 8(2):147-153.
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