Volume No. :   8

Issue No. :  1

Year :  2016

ISSN Print :  0975-234X

ISSN Online :  0975-4377


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A Review: Determination of Clopidogrel Bisulphate in Biological Fluid and Pharmaceutical Dosage Forms



Address:   Pankaj Savani1*, Vineet Jain2, Hasumati Raj1, Sagar Patel1
1Department of Quality Assurance, Shree Dhanvantary Pharmacy College, Kim, Dist: Surat, Gujarat, India. 394110
2Department of Pharmacognosy, Shree Dhanvantary Pharmacy College, Kim, Dist: Surat, Gujarat, India. 394110
*Corresponding Author
DOI No: 10.5958/0975-4377.2016.00009.4

ABSTRACT:
Clopidogrel Bisulphate is a mainly use in Anti platelet agent as a ADP receptor blocker and administration of oral tablet dosage form. Chemically, it is Methyl 2-(2- Chlorophenyl) -2-(6, 7-dihydro thieno [3,2-C] Pyridine-5(4H)-yl) Acetate sulphate. It is used in the treatment of various cardiovascular diseases like Ischemic stroke as well as in Glomerular inflammation, Myocardial infarction, Atherosclerosis disease, Unstable Angina. An extensive survey of the literature published in various analytical and pharmaceutical chemistry related journals has been conducted and the instrumental analytical methods which were developed and used for determination as single or combination with other drugs in bulk drugs, formulations and biological fluids have been reviewed. These reviews of analytical methods including Spectrophotometric methods like Spectrophotometry, Chromatographic method including HPLC, HPTLC were reported.
KEYWORDS:
Clopidogrel Bisulphate, Analytical methods, Compendial Method, UV Spectroscopic method, Chromatographic methods.
Cite:
Pankaj Savani, Vineet Jain, Hasumati Raj, Sagar Patel. A Review: Determination of Clopidogrel Bisulphate in Biological Fluid and Pharmaceutical Dosage Forms. Res. J. Pharm. Dosage Form. & Tech. 8(1): Jan.-Mar. 2016; Page 66-70.
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