Volume No. :   6

Issue No. :  1

Year :  2014

ISSN Print :  0975-234X

ISSN Online :  0975-4377


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Aquasome: A Self-Assembling Supramolecular And Nanoparticulate Carrier System For Bio-Actives



Address:   N.K. Hada* and Ashawat M.S.
Laureate Institute of Pharmacy, Kathog, Hamirpur, Himachal Pradesh
*Corresponding Author
DOI No:

ABSTRACT:
Recent advancement within the space of biotechnology and genetics science has resulted in promotion of proteins and peptides as a major class of therapeutic agents. Administration of the bioactive molecules in their active state has been an enormous task to the pharmaceutical additionally as biotechnological industries. Drug associated challenges like appropriate route of drug delivery, physical and chemical instability, poor bioavailability, and potentially serious side effects of these bioengineered molecules are some potential limitations on their successful formulation. While developing these formulations, the goal is to obtain delivery system with optimized drug loading and release properties, long shelf-life and low toxicity. Several types of NDDS have been developed for last few decades which are aquasome, liposomes, niosomes, pharmacosomes, microparticles, nanoparticles, dendrimers, multiple emulsions, microemulsions, osmotic-modulated drug delivery system, transdermal-therapeutic system, self-regulated and brain-targated drug delivery system etc. consider as promising carrier for the delivery of a broad range of molecules includes xenobiotics, viral antigens, haemoglobin and insulin. Whereever medicine area allowed to absorb on the surface of nanoparticales within the presence of carbohydrates film that prevent soft drugs from changing shaped and being damaged when surface bound.
KEYWORDS:
Water bodies, Self-assembling carrier system, Nano particulate , Nanocrystalline core, supramolecule, bio-actives etc.
Cite:
N.K. Hada, Ashawat M.S. Aquasome: A Self-Assembling Supramolecular And Nanoparticulate Carrier System For Bio-Actives. Res. J. Pharm. Dosage Form. & Tech. 6(1): Jan.-Mar. 2014; Page 50-53.
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