Volume No. :   5

Issue No. :  2

Year :  2013

ISSN Print :  0975-234X

ISSN Online :  0975-4377


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Transdermal Drug Delivery System: A Review



Address:   Bhakti R. Chorghe1*, Swapnil T. Deshpande2, Rohit D. Shah1, Swati S. Korabu1, Sagar V. Motarwar3
1Sinhgad College of Pharmacy, Vadgaon (Bk.), Pune – 411 041
2SCSSS’s Sitabai Thite College of Pharmacy, Shirur, Pune – 412 210
3Smt. Kashibai Navale College of Pharmacy, Kondhwa (Bk.), Pune – 411 048
*Corresponding Author
DOI No:

ABSTRACT:
Transdermal therapeutic systems, or transdermal patches, facilitate controlled release of active ingredients through the skin and into the systemic circulation. Drugs administered through such systems escape first pass metabolism and steady state is maintained similar to a continuous intravenous infusion for up to several days. The transdermal route of drug delivery has attracted researchers due to many biomedical advantages associated with it. However, excellent impervious nature of skin is the greatest challenge that has to be overcome for successfully delivering drug molecules to the systemic circulation by this route. This article gives a brief overview over principles behind transdermal drug delivery, as well as the advantages and disadvantages of transdermal therapeutic systems and the recent innovations in the field of transdermal drug delivery and also describes the methods of preparation of different types of transdermal patches, evaluation parameters and some available marketed products.
KEYWORDS:
Transdermal drug delivery system, transdermal patches, evaluation of Transdermal system, skin.
Cite:
Bhakti R. Chorghe, Swapnil T. Deshpande, Rohit D. Shah, Swati S. Korabu, Sagar V. Motarwar. Transdermal Drug Delivery System: A Review. Research J. Pharma. Dosage Forms and Tech. 2013; 5(2): 65-69.
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