Volume No. :   2

Issue No. :  6

Year :  2010

ISSN Print :  0975-234X

ISSN Online :  0975-4377


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Evaluation of Seed Mucilage of Hibiscus Sabdariffa Linn as Tablet Binder



Address:   Ch. Anupama1*, P. Padmakumari1, K. Abbulu1, Arti Mohan1 and A. Ppratyusha2
1Malla Reddy Institute of Pharmaceutical Sciences, Andhra Pradesh, India
2CMR College of Pharmacy, Andhra Pradesh, India
*Corresponding Author:
DOI No:

ABSTRACT:
The aim of present study is to evaluate the mucilage of Hibiscus sabdariffa seeds as tablet binder using Diclofenac sodium as standard drug .To the best of our knowledge no significant work has been reported on seed mucilage as tablet binder. Physicochemical characteristics of mucilage were studied which confirmed the mucilage nature. The tablets were prepared by wet granulation technique using mucilage as tablet binder. The prepared tablets were evaluated for their granulating and binding properties. The tablets exhibited good uniformity and drug release was more than 85% in 90 min. Tablet’s hardness and disintegration time was increased with increasing binder concentration and friability values were decreased with increase in binder concentration. All these confirm the use of Hibiscus sabdariffa as binder in tablet formulation.
KEYWORDS:
Hibiscus sabdariffa, mucilage, binder.
Cite:
Ch. Anupama, P. Padmakumari, K. Abbulu, Arti Mohan, A. Ppratyusha. Evaluation of Seed Mucilage of Hibiscus Sabdariffa Linn as Tablet Binder. Research J. Pharma. Dosage Forms and Tech. 2010; 2(6): 381-383.
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