Volume No. :   1

Issue No. :  2

Year :  2009

ISSN Print :  0975-234X

ISSN Online :  0975-4377


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Anti-Inflammatory Activity of Ethanolic and Acetone Extracts of Bauhnia variegate



Address:   D Sheshadri Shekar* C Velmurugan, G Ramakrishnan and B Vivek
Department of Pharmacology, Sri K .V College of Pharmacy, M.G.Road, Chickballapur-562101.
*Corresponding Author
DOI No:

ABSTRACT:
The ethanolic and acetone extracts of Bauhnia variegate bark was examined for anti-inflammatory in experimental animals. In this study both acute and sub-acute inflammation models were used to evaluate the anti-inflammatory activity of the Bauhnia variegate. In acute model carrageenan was used to induce inflammation in rat hind paw and in sub-acute inflammation, cotton pellet induced granuloma was performed. The bark of ethanolic and acetone extracts of bauhnia variegate at the doses of 400 mg/kg shows significant (p<0.001) inhibition of inflammation against both acute and sub-acute anti-inflammatory model. The percentage inhibition of ethanolic and acetone extract of Bauhnia variegate both acute and sub-acute anti-inflammatory model was 35.29%, 43.14% and 33.53%, 42.20% respectively. According to our results both the extracts of Bauhnia variegate in doses of 400 mg/kg reveals anti-inflammatory activity and supports tribal claim.
KEYWORDS:
Anti-inflammatory, Carrageenan, Cotton pellet granuloma and Bauhnia variegate.
Cite:
D Sheshadri Shekar, C Velmurugan, G Ramakrishnan , B Vivek. Anti-Inflammatory Activity of Ethanolic and Acetone Extracts of Bauhnia variegate. Research J. Pharma. Dosage Forms and Tech. 2009; 1(2): 97-99.
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